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CYP2C19 genotype-guided antiplatelet therapy: promises and pitfalls

Pharmacogenetic variants can alter the mechanism of action (pharmacodynamic gene variants) or kinetic processes such as absorption, distribution, metabolism and elimination (pharmacokinetic gene variants). Many initial successes in precision medicine occurred in the context of genes encoding the cyt...

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Detalles Bibliográficos
Autores principales: Ellithi, Moataz, Baye, Jordan, Wilke, Russell A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444625/
https://www.ncbi.nlm.nih.gov/pubmed/32723143
http://dx.doi.org/10.2217/pgs-2020-0046

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