Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018

We examined Massachusetts tuberculosis surveillance data from to 2009 to 2018. Of 1533 culture-confirmed cases, 190 (12.4%) demonstrated resistance to isoniazid including 32 (2.1%) with rifampin resistance. In multivariable analysis, isoniazid resistance increased significantly over time (per-year o...

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Autores principales: Eddy, Jared J, Gadani, Kavita M, Tibbs, Andrew, Bernardo, John, Cochran, Jennifer, White, Laura F, Horsburgh, C Robert, Jacobson, Karen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444736/
https://www.ncbi.nlm.nih.gov/pubmed/32855987
http://dx.doi.org/10.1093/ofid/ofaa300
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author Eddy, Jared J
Gadani, Kavita M
Tibbs, Andrew
Bernardo, John
Cochran, Jennifer
White, Laura F
Horsburgh, C Robert
Jacobson, Karen R
author_facet Eddy, Jared J
Gadani, Kavita M
Tibbs, Andrew
Bernardo, John
Cochran, Jennifer
White, Laura F
Horsburgh, C Robert
Jacobson, Karen R
author_sort Eddy, Jared J
collection PubMed
description We examined Massachusetts tuberculosis surveillance data from to 2009 to 2018. Of 1533 culture-confirmed cases, 190 (12.4%) demonstrated resistance to isoniazid including 32 (2.1%) with rifampin resistance. In multivariable analysis, isoniazid resistance increased significantly over time (per-year odds ratio = 1.07, 95% confidence interval = 1.01–1.13, P = .018) and was associated with younger age, foreign birth, and prior tuberculosis treatment.
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spelling pubmed-74447362020-08-26 Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018 Eddy, Jared J Gadani, Kavita M Tibbs, Andrew Bernardo, John Cochran, Jennifer White, Laura F Horsburgh, C Robert Jacobson, Karen R Open Forum Infect Dis Brief Reports We examined Massachusetts tuberculosis surveillance data from to 2009 to 2018. Of 1533 culture-confirmed cases, 190 (12.4%) demonstrated resistance to isoniazid including 32 (2.1%) with rifampin resistance. In multivariable analysis, isoniazid resistance increased significantly over time (per-year odds ratio = 1.07, 95% confidence interval = 1.01–1.13, P = .018) and was associated with younger age, foreign birth, and prior tuberculosis treatment. Oxford University Press 2020-07-18 /pmc/articles/PMC7444736/ /pubmed/32855987 http://dx.doi.org/10.1093/ofid/ofaa300 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Eddy, Jared J
Gadani, Kavita M
Tibbs, Andrew
Bernardo, John
Cochran, Jennifer
White, Laura F
Horsburgh, C Robert
Jacobson, Karen R
Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018
title Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018
title_full Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018
title_fullStr Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018
title_full_unstemmed Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018
title_short Increasing Drug Resistance Among Persons With Tuberculosis in Massachusetts, 2009–2018
title_sort increasing drug resistance among persons with tuberculosis in massachusetts, 2009–2018
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444736/
https://www.ncbi.nlm.nih.gov/pubmed/32855987
http://dx.doi.org/10.1093/ofid/ofaa300
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