Universality of clonal dynamics poses fundamental limits to identify stem cell self-renewal strategies

How adult stem cells maintain self-renewing tissues is commonly assessed by analysing clonal data from in vivo cell lineage-tracing assays. To identify strategies of stem cell self-renewal requires that different models of stem cell fate choice predict sufficiently different clonal statistics. Here,...

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Detalles Bibliográficos
Autores principales: Parigini, Cristina, Greulich, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444910/
https://www.ncbi.nlm.nih.gov/pubmed/32687057
http://dx.doi.org/10.7554/eLife.56532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444910/
https://www.ncbi.nlm.nih.gov/pubmed/32687057
http://dx.doi.org/10.7554/eLife.56532

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