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Universality of clonal dynamics poses fundamental limits to identify stem cell self-renewal strategies
How adult stem cells maintain self-renewing tissues is commonly assessed by analysing clonal data from in vivo cell lineage-tracing assays. To identify strategies of stem cell self-renewal requires that different models of stem cell fate choice predict sufficiently different clonal statistics. Here,...
Autores principales: | Parigini, Cristina, Greulich, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444910/ https://www.ncbi.nlm.nih.gov/pubmed/32687057 http://dx.doi.org/10.7554/eLife.56532 |
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