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Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences

Pineal dysgerminomas are sporadic pediatric intracranial tumors that usually grow as midline lesions around the third ventricle, most frequently the pineal gland and the pituitary regions of the brain. The severity of symptoms is dependent on the location of the lesion and can present with increased...

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Detalles Bibliográficos
Autores principales: Torres, Alcy R, Salvador, Carla, Mora, Mauricio D, Chavez, Wilson, Romero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444959/
https://www.ncbi.nlm.nih.gov/pubmed/32850234
http://dx.doi.org/10.7759/cureus.9365
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author Torres, Alcy R
Salvador, Carla
Mora, Mauricio D
Chavez, Wilson
Romero, Javier
author_facet Torres, Alcy R
Salvador, Carla
Mora, Mauricio D
Chavez, Wilson
Romero, Javier
author_sort Torres, Alcy R
collection PubMed
description Pineal dysgerminomas are sporadic pediatric intracranial tumors that usually grow as midline lesions around the third ventricle, most frequently the pineal gland and the pituitary regions of the brain. The severity of symptoms is dependent on the location of the lesion and can present with increased intracranial symptoms. We report a 20-year-old man who presented with new-onset headaches over the past month that would wake him from his sleep at night. The headaches, however, resolved completely one week prior to his first neurological evaluation. A thorough neurological examination was normal. A careful review of the literature does not show a case of a pineal tumor presenting with spontaneous regression of intracranial pressure, and therefore we would like to raise awareness among clinicians about this potential course. A delay in obtaining imaging could have been life-threatening; thus, we recommend a high index of suspicion when patients present with recent symptoms suggesting increased intracranial pressure. Our patient had an excellent outcome two years after his presentation, with appropriate management including drainage of the cerebrospinal fluid, chemotherapy, and radiotherapy.
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spelling pubmed-74449592020-08-25 Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences Torres, Alcy R Salvador, Carla Mora, Mauricio D Chavez, Wilson Romero, Javier Cureus Neurology Pineal dysgerminomas are sporadic pediatric intracranial tumors that usually grow as midline lesions around the third ventricle, most frequently the pineal gland and the pituitary regions of the brain. The severity of symptoms is dependent on the location of the lesion and can present with increased intracranial symptoms. We report a 20-year-old man who presented with new-onset headaches over the past month that would wake him from his sleep at night. The headaches, however, resolved completely one week prior to his first neurological evaluation. A thorough neurological examination was normal. A careful review of the literature does not show a case of a pineal tumor presenting with spontaneous regression of intracranial pressure, and therefore we would like to raise awareness among clinicians about this potential course. A delay in obtaining imaging could have been life-threatening; thus, we recommend a high index of suspicion when patients present with recent symptoms suggesting increased intracranial pressure. Our patient had an excellent outcome two years after his presentation, with appropriate management including drainage of the cerebrospinal fluid, chemotherapy, and radiotherapy. Cureus 2020-07-23 /pmc/articles/PMC7444959/ /pubmed/32850234 http://dx.doi.org/10.7759/cureus.9365 Text en Copyright © 2020, Torres et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Torres, Alcy R
Salvador, Carla
Mora, Mauricio D
Chavez, Wilson
Romero, Javier
Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences
title Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences
title_full Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences
title_fullStr Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences
title_full_unstemmed Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences
title_short Pineal Dysgerminoma: A Misleading Clinical Course With Potential Life-Threatening Consequences
title_sort pineal dysgerminoma: a misleading clinical course with potential life-threatening consequences
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444959/
https://www.ncbi.nlm.nih.gov/pubmed/32850234
http://dx.doi.org/10.7759/cureus.9365
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