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Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher

Background Primary percutaneous coronary intervention (PCI) is a treatment of choice for patients with ST-segment elevation myocardial infarction (STEMI). Of the various risk stratification scores that have been introduced, the thrombolysis in myocardial infarction (TIMI) score is among the most use...

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Autores principales: Talreja, Kanhiyalal, Sheikh, Khalil, Rahman, Azizur, Parkash, Chander, Khan, Abid Abbas, Ahmed, Faisal, Karim, Musa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444986/
https://www.ncbi.nlm.nih.gov/pubmed/32850228
http://dx.doi.org/10.7759/cureus.9356
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author Talreja, Kanhiyalal
Sheikh, Khalil
Rahman, Azizur
Parkash, Chander
Khan, Abid Abbas
Ahmed, Faisal
Karim, Musa
author_facet Talreja, Kanhiyalal
Sheikh, Khalil
Rahman, Azizur
Parkash, Chander
Khan, Abid Abbas
Ahmed, Faisal
Karim, Musa
author_sort Talreja, Kanhiyalal
collection PubMed
description Background Primary percutaneous coronary intervention (PCI) is a treatment of choice for patients with ST-segment elevation myocardial infarction (STEMI). Of the various risk stratification scores that have been introduced, the thrombolysis in myocardial infarction (TIMI) score is among the most used modalities. Patients with a TIMI score of five or higher are classified as high-risk patients with higher rates of adverse events. Therefore, this study aimed to determine the rate of adverse events after primary PCI in patients presenting with STEMI and a TIMI score of five or higher. Methodology This descriptive study was conducted at the cardiology department of the Liaquat National Hospital, Karachi, from February 2018 to August 2018. The patients included in this study consisted of a total of 150 men and women who presented to the ED with concerns of chest pain and were diagnosed with STEMI and had a TIMI score of five or higher. Consultant cardiologists performed primary PCI procedures, and any post-procedure adverse events were recorded during the patients’ hospital stays (up to one week), including mortality, heart failure, cardiogenic shock, and ventricular arrhythmias. Results The study population was 83.3% male and 16.7% female patients, and the mean age was 54.0 ± 9.4 years. The mean BMI was 27.34 ± 2.76 kg/m(2). The mean TIMI score was 9.19 ± 2.71, with a TIMI score higher than eight for 52.7% of patients. Death was observed in 18.7% of cases, heart failure in 21.3% of cases, cardiogenic shock in 13.3% of cases, and ventricular arrhythmia in 22.0% of cases. Conclusion A TIMI risk score of five or higher can identify patients at high risk not only for mortality, but also for heart failure, cardiogenic shock, and ventricular arrhythmias.
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spelling pubmed-74449862020-08-25 Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher Talreja, Kanhiyalal Sheikh, Khalil Rahman, Azizur Parkash, Chander Khan, Abid Abbas Ahmed, Faisal Karim, Musa Cureus Cardiology Background Primary percutaneous coronary intervention (PCI) is a treatment of choice for patients with ST-segment elevation myocardial infarction (STEMI). Of the various risk stratification scores that have been introduced, the thrombolysis in myocardial infarction (TIMI) score is among the most used modalities. Patients with a TIMI score of five or higher are classified as high-risk patients with higher rates of adverse events. Therefore, this study aimed to determine the rate of adverse events after primary PCI in patients presenting with STEMI and a TIMI score of five or higher. Methodology This descriptive study was conducted at the cardiology department of the Liaquat National Hospital, Karachi, from February 2018 to August 2018. The patients included in this study consisted of a total of 150 men and women who presented to the ED with concerns of chest pain and were diagnosed with STEMI and had a TIMI score of five or higher. Consultant cardiologists performed primary PCI procedures, and any post-procedure adverse events were recorded during the patients’ hospital stays (up to one week), including mortality, heart failure, cardiogenic shock, and ventricular arrhythmias. Results The study population was 83.3% male and 16.7% female patients, and the mean age was 54.0 ± 9.4 years. The mean BMI was 27.34 ± 2.76 kg/m(2). The mean TIMI score was 9.19 ± 2.71, with a TIMI score higher than eight for 52.7% of patients. Death was observed in 18.7% of cases, heart failure in 21.3% of cases, cardiogenic shock in 13.3% of cases, and ventricular arrhythmia in 22.0% of cases. Conclusion A TIMI risk score of five or higher can identify patients at high risk not only for mortality, but also for heart failure, cardiogenic shock, and ventricular arrhythmias. Cureus 2020-07-23 /pmc/articles/PMC7444986/ /pubmed/32850228 http://dx.doi.org/10.7759/cureus.9356 Text en Copyright © 2020, Talreja et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Talreja, Kanhiyalal
Sheikh, Khalil
Rahman, Azizur
Parkash, Chander
Khan, Abid Abbas
Ahmed, Faisal
Karim, Musa
Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher
title Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher
title_full Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher
title_fullStr Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher
title_full_unstemmed Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher
title_short Outcomes of Primary Percutaneous Coronary Intervention in Patients With a Thrombolysis in Myocardial Infarction Score of Five or Higher
title_sort outcomes of primary percutaneous coronary intervention in patients with a thrombolysis in myocardial infarction score of five or higher
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444986/
https://www.ncbi.nlm.nih.gov/pubmed/32850228
http://dx.doi.org/10.7759/cureus.9356
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