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Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine

OBJECTIVES: Gastrointestinal hormones contribute to the beneficial effects of Roux-en-Y gastric bypass surgery (RYGB) on glycemic control. Secretin is secreted from duodenal S cells in response to low luminal pH, but it is unknown whether its secretion is altered after RYGB and if secretin contribut...

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Detalles Bibliográficos
Autores principales: Modvig, Ida M., Andersen, Daniel B., Grunddal, Kaare V., Kuhre, Rune E., Martinussen, Christoffer, Christiansen, Charlotte B., Ørskov, Cathrine, Larraufie, Pierre, Kay, Richard G., Reimann, Frank, Gribble, Fiona M., Hartmann, Bolette, Bojsen-Møller, Kirstine N., Madsbad, Sten, Wewer Albrechtsen, Nicolai J., Holst, Jens J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445113/
https://www.ncbi.nlm.nih.gov/pubmed/32015474
http://dx.doi.org/10.1038/s41366-020-0541-7