Cargando…

Identification of a hotspot on PD-L1 for pH-dependent binding by monoclonal antibodies for tumor therapy

Detalles Bibliográficos
Autores principales:	Liu, Hongchuan, Bi, Xiaoshan, Zhou, Yuehua, Shi, Rui, Yao, Sheng, Qi, Jianxun, Feng, Hui, Feng, Meiqing, Yan, Jinghua, Tan, Shuguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445246/ https://www.ncbi.nlm.nih.gov/pubmed/32839442 http://dx.doi.org/10.1038/s41392-020-00254-z

Ejemplares similares

Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy
por: Liu, Hongchuan, et al.
Publicado: (2019)

The FG Loop of PD-1 Serves as a “Hotspot” for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy
por: Chen, Danqing, et al.
Publicado: (2019)

The identification of a CD47-blocking “hotspot” and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination
por: Shi, Rui, et al.
Publicado: (2020)

Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab
por: Tan, Shuguang, et al.
Publicado: (2017)

Crystal clear: visualizing the intervention mechanism of the PD-1/PD-L1 interaction by two cancer therapeutic monoclonal antibodies
por: Tan, Shuguang, et al.
Publicado: (2016)

Characterization of the high-affinity anti-CTLA-4 monoclonal antibody JS007 for immune checkpoint therapy of cancer
por: Guan, Jiawei, et al.
Publicado: (2022)

PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy
por: Lu, Dan, et al.
Publicado: (2022)

Seeing is believing: anti-PD-1/PD-L1 monoclonal antibodies in action for checkpoint blockade tumor immunotherapy
por: Tan, Shuguang, et al.
Publicado: (2016)

Inhibition of PCSK9 enhances the antitumor effect of PD-1 inhibitor in colorectal cancer by promoting the infiltration of CD8(+) T cells and the exclusion of Treg cells
por: Wang, Rui, et al.
Publicado: (2022)

Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
por: He, Mengnan, et al.
Publicado: (2017)

An unexpected N-terminal loop in PD-1 dominates binding by nivolumab
por: Tan, Shuguang, et al.
Publicado: (2017)

A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT
por: Fu, Zhihao, et al.
Publicado: (2021)

A Comparison of Murine PD-1 and PD-L1 Monoclonal Antibodies
por: Bu, Melissa T., et al.
Publicado: (2022)

Method Development and Qualification of pH-Based CEX UPLC Method for Monoclonal Antibodies
por: Bhatt, Mithun, et al.
Publicado: (2022)

Granulomatous myositis induced by anti–PD-1 monoclonal antibodies
por: Uchio, Naohiro, et al.
Publicado: (2018)

A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus
por: Li, Yan, et al.
Publicado: (2022)

Large-scale generative simulation artificial intelligence: The next hotspot
por: Wang, Qi, et al.
Publicado: (2023)

The combination of anti-KIR monoclonal antibodies with anti-PD-1/PD-L1 monoclonal antibodies could be a critical breakthrough in overcoming tumor immune escape in NSCLC
por: He, Yayi, et al.
Publicado: (2018)

De novo isolation of antibodies with pH-dependent binding properties
por: Bonvin, Pauline, et al.
Publicado: (2015)

Isolation of Monoclonal Antibodies from Zika Virus-Infected Patient Samples
por: Wang, Qihui, et al.
Publicado: (2020)

Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses
por: Xiao, Haixia, et al.
Publicado: (2019)

Binding of omeprazole to protein targets identified by monoclonal antibodies
por: Cartee, Naw May Pearl, et al.
Publicado: (2020)

Role of Domain–Domain Interactions on the Self-Association and Physical Stability of Monoclonal Antibodies: Effect of pH and Salt
por: Xu, Amy Y., et al.
Publicado: (2023)

Application of NMR and Chemometric Analyses to Better Understand the Quality Attributes in pH and Thermally Degraded Monoclonal Antibodies
por: Beaumont, Victor A., et al.
Publicado: (2023)

Disorder of Coagulation-Fibrinolysis System: An Emerging Toxicity of Anti-PD-1/PD-L1 Monoclonal Antibodies
por: Sato, Ryo, et al.
Publicado: (2019)

Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function
por: Choi, Jin Wook, et al.
Publicado: (2020)

Human monoclonal antibodies and monoclonal antibody multispecificity.
por: Campbell, A. M., et al.
Publicado: (1987)

pH Regulator on Digital Microfluidics with Pico-Dosing Technique
por: Li, Haoran, et al.
Publicado: (2023)

Diosgenin promotes antitumor immunity and PD-1 antibody efficacy against melanoma by regulating intestinal microbiota
por: Dong, Mengxue, et al.
Publicado: (2018)

Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H-binding protein
por: Peschiera, Ilaria, et al.
Publicado: (2019)

Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor
por: Liu, Jingxian, et al.
Publicado: (2019)

A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin
por: Yu, Fei, et al.
Publicado: (2017)

Identification of a monoclonal antibody that targets PD-1 in a manner requiring PD-1 Asn58 glycosylation
por: Wang, Mingzhu, et al.
Publicado: (2019)

Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma
por: Faiena, Izak, et al.
Publicado: (2018)

Neisseria meningitidis factor H binding protein bound to monoclonal antibody JAR5: implications for antibody synergy
por: Malito, Enrico, et al.
Publicado: (2016)

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
por: Wu, Yan, et al.
Publicado: (2020)

Monoclonal Antibodies to Meningococcal Factor H Binding Protein with Overlapping Epitopes and Discordant Functional Activity
por: Giuntini, Serena, et al.
Publicado: (2012)

A low pH enzyme linked immunoassay using two monoclonal antibodies for the serological detection and monitoring of breast cancer.
por: Dhokia, B., et al.
Publicado: (1986)

Protein A chromatography increases monoclonal antibody aggregation rate during subsequent low pH virus inactivation hold
por: Mazzer, Alice R., et al.
Publicado: (2015)

Preparation, identification, and clinical application of anti-HBs monoclonal antibody that binds both wild-type and immune escape mutant HBsAgs
por: Li, Fanghe, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_asmja0br0m0mbij36fdvqafg35