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A biphasic nanohydroxyapatite/calcium sulphate carrier containing Rifampicin and Isoniazid for local delivery gives sustained and effective antibiotic release and prevents biofilm formation
Long term multiple systemic antibiotics form the cornerstone in the treatment of bone and joint tuberculosis, often combined with local surgical eradication. Implanted carriers for local drug delivery have recently been introduced to overcome some of the limitations associated with conventional trea...
Autores principales: | Qayoom, Irfan, Verma, Rahul, Murugan, Prem Anand, Raina, Deepak Bushan, Teotia, Arun Kumar, Matheshwaran, Saravanan, Nair, Nisanth N., Tägil, Magnus, Lidgren, Lars, Kumar, Ashok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445265/ https://www.ncbi.nlm.nih.gov/pubmed/32839480 http://dx.doi.org/10.1038/s41598-020-70726-3 |
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