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DNA damage response and preleukemic fusion genes induced by ionizing radiation in umbilical cord blood hematopoietic stem cells

There is clear evidence that ionizing radiation (IR) causes leukemia. For many types of leukemia, the preleukemic fusion genes (PFG), as consequences of DNA damage and chromosomal translocations, occur in hematopoietic stem and progenitor cells (HSPC) in utero and could be detected in umbilical cord...

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Detalles Bibliográficos
Autores principales:	Kosik, Pavol, Durdik, Matus, Jakl, Lukas, Skorvaga, Milan, Markova, Eva, Vesela, Gabriela, Vokalova, Lenka, Kolariková, Lucia, Horvathova, Eva, Kozics, Katarina, Belyaev, Igor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445283/ https://www.ncbi.nlm.nih.gov/pubmed/32839487 http://dx.doi.org/10.1038/s41598-020-70657-z

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