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Osthole Reduces Mouse IOP Associated With Ameliorating Extracellular Matrix Expression of Trabecular Meshwork Cell

PURPOSE: Elevation of IOP in POAG is thought to involve excessive accumulation of extracellular matrix in the trabecular meshwork (TM), leading to an increase in outflow resistance of the aqueous humor. Osthole, a coumarin derivative extracted from the fruit of a variety of plants, such as Cnidium m...

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Detalles Bibliográficos
Autores principales: Fan, Yuchen, Wei, Jiahong, Guo, Li, Zhao, Siyu, Xu, Chenyu, Sun, Hao, Guo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445364/
https://www.ncbi.nlm.nih.gov/pubmed/32821914
http://dx.doi.org/10.1167/iovs.61.10.38