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The lncRNA H19 binding to let‐7b promotes hippocampal glial cell activation and epileptic seizures by targeting Stat3 in a rat model of temporal lobe epilepsy

OBJECTIVES: Glial cell activation contributes to the inflammatory response and occurrence of epilepsy. Our preliminary study demonstrated that the long non‐coding RNA, H19, promotes hippocampal glial cell activation during epileptogenesis. However, the precise mechanisms underlying this effect remai...

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Detalles Bibliográficos
Autores principales: Han, Chun‐Lei, Liu, Yun‐Peng, Guo, Chen‐Jia, Du, Ting‐Ting, Jiang, Ying, Wang, Kai‐Liang, Shao, Xiao‐Qiu, Meng, Fan‐Gang, Zhang, Jian‐Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445408/
https://www.ncbi.nlm.nih.gov/pubmed/32648622
http://dx.doi.org/10.1111/cpr.12856