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Cilostazol ameliorates diabetic nephropathy by inhibiting high-glucose-induced apoptosis
Diabetic nephropathy (DN) is a hyperglycemia-induced progressive development of renal insufficiency. Excessive glucose can increase mitochondrial reactive oxygen species (ROS) and induce cell damage, causing mitochondrial dysfunction. Our previous study indicated that cilostazol (CTZ) can reduce ROS...
Autores principales: | Chian, Chien-Wen, Lee, Yung-Shu, Lee, Yi-Ju, Chen, Ya-Hui, Wang, Chi-Ping, Lee, Wen-Chin, Lee, Huei-Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445481/ https://www.ncbi.nlm.nih.gov/pubmed/32830147 http://dx.doi.org/10.4196/kjpp.2020.24.5.403 |
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