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Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era

INTRODUCTION: The scope of the impact of the coronavirus disease 2019 (COVID-19) pandemic on living donor kidney transplantation (LDKT) practices is not well defined. METHODS: We surveyed US transplant programs to assess practices, strategies, and barriers to living LDKT during the COVID-19 pandemic...

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Autores principales: Lentine, Krista L., Vest, Luke S., Schnitzler, Mark A., Mannon, Roslyn B., Kumar, Vineeta, Doshi, Mona D., Cooper, Matthew, Mandelbrot, Didier A., Harhay, Meera N., Josephson, Michelle A., Caliskan, Yasar, Sharfuddin, Asif, Kasiske, Bertram L., Axelrod, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445484/
https://www.ncbi.nlm.nih.gov/pubmed/32864513
http://dx.doi.org/10.1016/j.ekir.2020.08.017
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author Lentine, Krista L.
Vest, Luke S.
Schnitzler, Mark A.
Mannon, Roslyn B.
Kumar, Vineeta
Doshi, Mona D.
Cooper, Matthew
Mandelbrot, Didier A.
Harhay, Meera N.
Josephson, Michelle A.
Caliskan, Yasar
Sharfuddin, Asif
Kasiske, Bertram L.
Axelrod, David A.
author_facet Lentine, Krista L.
Vest, Luke S.
Schnitzler, Mark A.
Mannon, Roslyn B.
Kumar, Vineeta
Doshi, Mona D.
Cooper, Matthew
Mandelbrot, Didier A.
Harhay, Meera N.
Josephson, Michelle A.
Caliskan, Yasar
Sharfuddin, Asif
Kasiske, Bertram L.
Axelrod, David A.
author_sort Lentine, Krista L.
collection PubMed
description INTRODUCTION: The scope of the impact of the coronavirus disease 2019 (COVID-19) pandemic on living donor kidney transplantation (LDKT) practices is not well defined. METHODS: We surveyed US transplant programs to assess practices, strategies, and barriers to living LDKT during the COVID-19 pandemic. After institutional review board approval, the survey was distributed from 9 May 2020 to 30 May 2020 by e-mail and postings to professional society list-servs. Responses were stratified based on state COVID-19 cumulative incidence levels. RESULTS: Staff at 118 unique centers responded, representing 61% of US living donor recovery programs and 75% of LKDT volume in the prepandemic year. Overall, 66% reported that LDKT surgery was on hold (81% in “high” vs. 49% in “low” COVID-19 cumulative incidence states). A total of 36% reported that evaluation of new donor candidates had paused, 27% reported that evaluations were very much decreased (>0% to <25% typical), and 23% reported that evaluations were moderately decreased (25% to <50% typical). Barriers to LDKT surgery included program concerns for donor (85%) and recipient (75%) safety, patient concerns (56%), elective case restrictions (47%), and hospital administrative restrictions (48%). Programs with higher local COVID-19 cumulative incidence reported more barriers related to staff and resource diversion. Most centers continuing donor evaluations used remote strategies (video, 82%; telephone, 43%). As LDKT resumes, all programs will screen for COVID-19, although timeframe and modalities will vary. Recommendations for presurgical self-quarantine are also variable. CONCLUSION: The COVID-19 pandemic has had broad impacts on LDKT practice. Ongoing research and consensus building are needed to reduce barriers, to guide optimal practices, and to support safe restoration of LDKT across centers.
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spelling pubmed-74454842020-08-26 Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era Lentine, Krista L. Vest, Luke S. Schnitzler, Mark A. Mannon, Roslyn B. Kumar, Vineeta Doshi, Mona D. Cooper, Matthew Mandelbrot, Didier A. Harhay, Meera N. Josephson, Michelle A. Caliskan, Yasar Sharfuddin, Asif Kasiske, Bertram L. Axelrod, David A. Kidney Int Rep Clinical Research INTRODUCTION: The scope of the impact of the coronavirus disease 2019 (COVID-19) pandemic on living donor kidney transplantation (LDKT) practices is not well defined. METHODS: We surveyed US transplant programs to assess practices, strategies, and barriers to living LDKT during the COVID-19 pandemic. After institutional review board approval, the survey was distributed from 9 May 2020 to 30 May 2020 by e-mail and postings to professional society list-servs. Responses were stratified based on state COVID-19 cumulative incidence levels. RESULTS: Staff at 118 unique centers responded, representing 61% of US living donor recovery programs and 75% of LKDT volume in the prepandemic year. Overall, 66% reported that LDKT surgery was on hold (81% in “high” vs. 49% in “low” COVID-19 cumulative incidence states). A total of 36% reported that evaluation of new donor candidates had paused, 27% reported that evaluations were very much decreased (>0% to <25% typical), and 23% reported that evaluations were moderately decreased (25% to <50% typical). Barriers to LDKT surgery included program concerns for donor (85%) and recipient (75%) safety, patient concerns (56%), elective case restrictions (47%), and hospital administrative restrictions (48%). Programs with higher local COVID-19 cumulative incidence reported more barriers related to staff and resource diversion. Most centers continuing donor evaluations used remote strategies (video, 82%; telephone, 43%). As LDKT resumes, all programs will screen for COVID-19, although timeframe and modalities will vary. Recommendations for presurgical self-quarantine are also variable. CONCLUSION: The COVID-19 pandemic has had broad impacts on LDKT practice. Ongoing research and consensus building are needed to reduce barriers, to guide optimal practices, and to support safe restoration of LDKT across centers. Elsevier 2020-08-25 /pmc/articles/PMC7445484/ /pubmed/32864513 http://dx.doi.org/10.1016/j.ekir.2020.08.017 Text en © 2020 International Society of Nephrology. Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Clinical Research
Lentine, Krista L.
Vest, Luke S.
Schnitzler, Mark A.
Mannon, Roslyn B.
Kumar, Vineeta
Doshi, Mona D.
Cooper, Matthew
Mandelbrot, Didier A.
Harhay, Meera N.
Josephson, Michelle A.
Caliskan, Yasar
Sharfuddin, Asif
Kasiske, Bertram L.
Axelrod, David A.
Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era
title Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era
title_full Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era
title_fullStr Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era
title_full_unstemmed Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era
title_short Survey of US Living Kidney Donation and Transplantation Practices in the COVID-19 Era
title_sort survey of us living kidney donation and transplantation practices in the covid-19 era
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445484/
https://www.ncbi.nlm.nih.gov/pubmed/32864513
http://dx.doi.org/10.1016/j.ekir.2020.08.017
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