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Design of RNA hairpin modules that predictably tune translation in yeast

Modular parts for tuning translation are prevalent in prokaryotic synthetic biology but lacking for eukaryotic synthetic biology. Working in Saccharomyces cerevisiae yeast, we here describe how hairpin RNA structures inserted into the 5′ untranslated region (5′UTR) of mRNAs can be used to tune expre...

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Detalles Bibliográficos
Autores principales: Weenink, Tim, van der Hilst, Jelle, McKiernan, Robert M, Ellis, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445769/
https://www.ncbi.nlm.nih.gov/pubmed/32995525
http://dx.doi.org/10.1093/synbio/ysy019