Exploiting the sequence diversity of TALE-like repeats to vary the strength of dTALE-promoter interactions

Designer transcription activator-like effectors (dTALEs) are programmable transcription factors used to regulate user-defined promoters. The TALE DNA-binding domain is a tandem series of amino acid repeats that each bind one DNA base. Each repeat is 33–35 amino acids long. A residue in the center of...

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Detalles Bibliográficos
Autores principales: de Lange, Orlando, Schandry, Niklas, Wunderlich, Markus, Berendzen, Kenneth Wayne, Lahaye, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445789/
https://www.ncbi.nlm.nih.gov/pubmed/32995505
http://dx.doi.org/10.1093/synbio/ysx004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445789/
https://www.ncbi.nlm.nih.gov/pubmed/32995505
http://dx.doi.org/10.1093/synbio/ysx004

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