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Exploiting the sequence diversity of TALE-like repeats to vary the strength of dTALE-promoter interactions
Designer transcription activator-like effectors (dTALEs) are programmable transcription factors used to regulate user-defined promoters. The TALE DNA-binding domain is a tandem series of amino acid repeats that each bind one DNA base. Each repeat is 33–35 amino acids long. A residue in the center of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445789/ https://www.ncbi.nlm.nih.gov/pubmed/32995505 http://dx.doi.org/10.1093/synbio/ysx004 |