Cargando…
Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors
Tumor targeting by genetically modified mesenchymal stromal/stem cells (MSCs) carrying anti-cancer molecules represents a promising cell-based strategy. We previously showed that the pro-apoptotic agent tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can be successfully delivered by...
Autores principales: | Golinelli, Giulia, Grisendi, Giulia, Prapa, Malvina, Bestagno, Marco, Spano, Carlotta, Rossignoli, Filippo, Bambi, Franco, Sardi, Iacopo, Cellini, Monica, Horwitz, Edwin M., Feletti, Alberto, Pavesi, Giacomo, Dominici, Massimo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445885/ https://www.ncbi.nlm.nih.gov/pubmed/30464207 http://dx.doi.org/10.1038/s41417-018-0062-x |
Ejemplares similares
-
A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing
por: Prapa, Malvina, et al.
Publicado: (2015) -
GD2 CAR T cells against human glioblastoma
por: Prapa, Malvina, et al.
Publicado: (2021) -
Anti-GD2 CAR MSCs against metastatic Ewing's sarcoma
por: Golinelli, Giulia, et al.
Publicado: (2021) -
Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy
por: Rossignoli, Filippo, et al.
Publicado: (2018) -
Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer
por: Spano, Carlotta, et al.
Publicado: (2019)