Cargando…

Impact of retrieved lymph node count on short-term complications in patients with gastric cancer

BACKGROUND: It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and short-term complications after radical surgery. METHODS: A total of 1487 consecut...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Feng, Liu, Song, Song, Peng, Zhang, Chen, Liu, Zhijian, Guan, Wenxian, Wang, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446131/
https://www.ncbi.nlm.nih.gov/pubmed/32838799
http://dx.doi.org/10.1186/s12957-020-02000-9
_version_ 1783574108337864704
author Sun, Feng
Liu, Song
Song, Peng
Zhang, Chen
Liu, Zhijian
Guan, Wenxian
Wang, Meng
author_facet Sun, Feng
Liu, Song
Song, Peng
Zhang, Chen
Liu, Zhijian
Guan, Wenxian
Wang, Meng
author_sort Sun, Feng
collection PubMed
description BACKGROUND: It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and short-term complications after radical surgery. METHODS: A total of 1487 consecutive GC patients between January 2016 and December 2018 at Nanjing Drum Tower Hospital were retrospectively analyzed. Univariate analyses were performed to elucidate the association between RLN count and postoperative complications. We further identified clinical factors that might affect the RLN count. RESULTS: Among all of the patients, postoperative complications occurred in 435 (29.3%) patients. The mean RLN count was 25.1, and 864 (58.1%) patients were diagnosed with lymph node metastasis. Univariate analyses showed no significant difference between RLN count and postoperative complications (both overall and stratified by CDC grade). Univariate and multivariate analyses further revealed that type of resection, tumor invasion, and lymph node metastasis were associated with RLN count. CONCLUSIONS: The current study demonstrated that RLN count was not associated with postoperative short-term complications following gastrectomy of GC, which provided a rationale for the determination of a proper RLN count of curative gastrectomy.
format Online
Article
Text
id pubmed-7446131
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-74461312020-08-26 Impact of retrieved lymph node count on short-term complications in patients with gastric cancer Sun, Feng Liu, Song Song, Peng Zhang, Chen Liu, Zhijian Guan, Wenxian Wang, Meng World J Surg Oncol Research BACKGROUND: It is well established that retrieved lymph node (RLN) counts were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLN count and short-term complications after radical surgery. METHODS: A total of 1487 consecutive GC patients between January 2016 and December 2018 at Nanjing Drum Tower Hospital were retrospectively analyzed. Univariate analyses were performed to elucidate the association between RLN count and postoperative complications. We further identified clinical factors that might affect the RLN count. RESULTS: Among all of the patients, postoperative complications occurred in 435 (29.3%) patients. The mean RLN count was 25.1, and 864 (58.1%) patients were diagnosed with lymph node metastasis. Univariate analyses showed no significant difference between RLN count and postoperative complications (both overall and stratified by CDC grade). Univariate and multivariate analyses further revealed that type of resection, tumor invasion, and lymph node metastasis were associated with RLN count. CONCLUSIONS: The current study demonstrated that RLN count was not associated with postoperative short-term complications following gastrectomy of GC, which provided a rationale for the determination of a proper RLN count of curative gastrectomy. BioMed Central 2020-08-24 /pmc/articles/PMC7446131/ /pubmed/32838799 http://dx.doi.org/10.1186/s12957-020-02000-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Sun, Feng
Liu, Song
Song, Peng
Zhang, Chen
Liu, Zhijian
Guan, Wenxian
Wang, Meng
Impact of retrieved lymph node count on short-term complications in patients with gastric cancer
title Impact of retrieved lymph node count on short-term complications in patients with gastric cancer
title_full Impact of retrieved lymph node count on short-term complications in patients with gastric cancer
title_fullStr Impact of retrieved lymph node count on short-term complications in patients with gastric cancer
title_full_unstemmed Impact of retrieved lymph node count on short-term complications in patients with gastric cancer
title_short Impact of retrieved lymph node count on short-term complications in patients with gastric cancer
title_sort impact of retrieved lymph node count on short-term complications in patients with gastric cancer
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446131/
https://www.ncbi.nlm.nih.gov/pubmed/32838799
http://dx.doi.org/10.1186/s12957-020-02000-9
work_keys_str_mv AT sunfeng impactofretrievedlymphnodecountonshorttermcomplicationsinpatientswithgastriccancer
AT liusong impactofretrievedlymphnodecountonshorttermcomplicationsinpatientswithgastriccancer
AT songpeng impactofretrievedlymphnodecountonshorttermcomplicationsinpatientswithgastriccancer
AT zhangchen impactofretrievedlymphnodecountonshorttermcomplicationsinpatientswithgastriccancer
AT liuzhijian impactofretrievedlymphnodecountonshorttermcomplicationsinpatientswithgastriccancer
AT guanwenxian impactofretrievedlymphnodecountonshorttermcomplicationsinpatientswithgastriccancer
AT wangmeng impactofretrievedlymphnodecountonshorttermcomplicationsinpatientswithgastriccancer