Upregulation of METTL14 mediates the elevation of PERP mRNA N(6) adenosine methylation promoting the growth and metastasis of pancreatic cancer

BACKGROUND: Pancreatic cancer is one of the most lethal human cancers. N(6)-methyladenosine (m(6)A), a common eukaryotic mRNA modification, plays critical roles in both physiological and pathological processes. However, its role in pancreatic cancer remains elusive. METHODS: LC/MS was used to profil...

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Detalles Bibliográficos
Autores principales: Wang, Min, Liu, Jun, Zhao, Yan, He, Ruizhi, Xu, Xiaodong, Guo, Xingjun, Li, Xu, Xu, Simiao, Miao, Ji, Guo, Jianpin, Zhang, Hang, Gong, Jun, Zhu, Feng, Tian, Rui, Shi, Chengjian, Peng, Feng, Feng, Yechen, Yu, Shuo, Xie, Yu, Jiang, Jianxin, Li, Min, Wei, Wenyi, He, Chuan, Qin, Renyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446161/
https://www.ncbi.nlm.nih.gov/pubmed/32843065
http://dx.doi.org/10.1186/s12943-020-01249-8

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