Cargando…

Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis

BACKGROUND: The mechanisms by which only some rheumatoid arthritis (RA) patients respond favorably to TNF blockade are still poorly characterized. The goal of this study was to identify biological features that explain this differential response using a multilevel transcriptome analysis of the synov...

Descripción completa

Detalles Bibliográficos
Autores principales:	Julià, Antonio, Ávila, Gabriela, Celis, Raquel, Sanmartí, Raimon, Ramírez, Julio, Marsal, Sara, Cañete, Juan D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446220/ https://www.ncbi.nlm.nih.gov/pubmed/32843099 http://dx.doi.org/10.1186/s13075-020-02287-9

Ejemplares similares

Synovial lymphoid neogenesis is associated with IL-23 expression and disease activity in rheumatoid arthritis
por: Cañete, Juan D, et al.
Publicado: (2011)

Immature Blood Vessels in Rheumatoid Synovium Are Selectively Depleted in Response to Anti-TNF Therapy
por: Izquierdo, Elena, et al.
Publicado: (2009)

Differential expansion of T peripheral helper cells in early rheumatoid arthritis and osteoarthritis synovium
por: Murray-Brown, William, et al.
Publicado: (2022)

Immunopathologic characterization of ultrasound-defined synovitis in rheumatoid arthritis patients in clinical remission
por: Ramírez, Julio, et al.
Publicado: (2016)

Synovial fibroblast hyperplasia correlates with rheumatoid arthritis duration and activity and is partially reversed by anti-TNF therapy
por: Izquierdo, E, et al.
Publicado: (2010)

Synovial Immunohistological Biomarkers of the Classification of Undifferentiated Arthritis Evolving to Rheumatoid or Psoriatic Arthritis
por: Cuervo, Andrea, et al.
Publicado: (2021)

Differences in synovial fluid cytokine levels but not in synovial tissue cell infiltrate between anti-citrullinated peptide/protein antibody-positive and –negative rheumatoid arthritis patients
por: Gómez-Puerta, José A, et al.
Publicado: (2013)

Calprotectin and TNF trough serum levels identify power Doppler ultrasound synovitis in rheumatoid arthritis and psoriatic arthritis patients in remission or with low disease activity
por: Inciarte-Mundo, José, et al.
Publicado: (2016)

Patients with rheumatoid arthritis in clinical remission and ultrasound-defined active synovitis exhibit higher disease activity and increased serum levels of angiogenic biomarkers
por: Ramírez, Julio, et al.
Publicado: (2014)

The Synovium in Rheumatoid Arthritis
por: Hitchon, Carol A, et al.
Publicado: (2011)

Ectopic lymphoid neogenesis is strongly associated with activation of the IL-23 pathway in rheumatoid synovitis
por: Cañete, Juan D., et al.
Publicado: (2015)

Synovial cytokine expression in psoriatic arthritis and associations with lymphoid neogenesis and clinical features
por: Celis, Raquel, et al.
Publicado: (2012)

Therapy with soluble TNF receptor (etanercept) induces apoptosis in rheumatoid arthritis (RA) synovium
por: Catrina, AI, et al.
Publicado: (2003)

Upadacitinib for Patients with Rheumatoid Arthritis: A Comprehensive Review
por: Sanmartí, Raimon, et al.
Publicado: (2023)

Cells of the synovium in rheumatoid arthritis. Chondrocytes
por: Otero, Miguel, et al.
Publicado: (2007)

Cells of the synovium in rheumatoid arthritis. Macrophages
por: Kinne, Raimund W, et al.
Publicado: (2007)

Cells of the synovium in rheumatoid arthritis. T lymphocytes
por: Lundy, Steven K, et al.
Publicado: (2007)

Cells of the synovium in rheumatoid arthritis. Osteoclasts
por: Schett, Georg
Publicado: (2007)

TNF inhibitors induce discoid fibrosis in the sublining layers of the synovium with degeneration of synoviocytes in rheumatoid arthritis
por: Hirohata, Shunsei, et al.
Publicado: (2013)

Calprotectin strongly and independently predicts relapse in rheumatoid arthritis and polyarticular psoriatic arthritis patients treated with tumor necrosis factor inhibitors: a 1-year prospective cohort study
por: Inciarte-Mundo, José, et al.
Publicado: (2018)

Differing specificities and isotypes of anti-citrullinated peptide/protein antibodies in palindromic rheumatism and rheumatoid arthritis
por: Cabrera-Villalba, Sonia, et al.
Publicado: (2017)

Correction: Cells of the synovium in rheumatoid arthritis. Chondrocytes
por: Otero, Miguel, et al.
Publicado: (2008)

Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts
por: Müller-Ladner, Ulf, et al.
Publicado: (2007)

Cells of the synovium in rheumatoid arthritis. B cells
por: Mauri, Claudia, et al.
Publicado: (2007)

Cells of the synovium in rheumatoid arthritis. Dendritic cells
por: Lutzky, Viviana, et al.
Publicado: (2007)

Expression of galectin-3 in rheumatoid arthritis synovium
por: Neidhart, M, et al.
Publicado: (2002)

Palindromic Rheumatism: Just a Pre-rheumatoid Stage or Something Else?
por: Sanmartí, Raimon, et al.
Publicado: (2021)

Autoimmune Responses in the Rheumatoid Synovium
por: Toes, Rene E. M, et al.
Publicado: (2009)

Rheumatoid arthritis synovium contains plasmacytoid dendritic cells
por: Cavanagh, Lois L, et al.
Publicado: (2005)

Expression of cyclooxygenase-1 and -2 in rheumatoid arthritis synovium.
por: Lee, Y. H., et al.
Publicado: (2000)

Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
por: Zhang, Fan, et al.
Publicado: (2023)

Distinct synovial immunopathology in Behçet disease and psoriatic arthritis
por: Cañete, Juan D, et al.
Publicado: (2009)

A study on FoxP3 and Tregs in paired samples of peripheral blood and synovium in rheumatoid arthritis
por: Shalini P., Usha, et al.
Publicado: (2016)

Implications of Post-Translational Modifications in Autoimmunity with Emphasis on Citrullination, Homocitrullination and Acetylation for the Pathogenesis, Diagnosis and Prognosis of Rheumatoid Arthritis
por: Haro, Isabel, et al.
Publicado: (2022)

Monocyte migration to the synovium in rheumatoid arthritis patients treated with adalimumab
por: Herenius, M M J, et al.
Publicado: (2011)

Synergistically targeting synovium STING pathway for rheumatoid arthritis treatment
por: Shen, Haotian, et al.
Publicado: (2022)

Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis
por: Prieto-Potin, Iván, et al.
Publicado: (2015)

Cytokine expression in synovial tissue of psoriatic arthritis and its relationship with lymphoid neogenesis, disease activity and erosive disease: a longitudinal study
por: Celis, R, et al.
Publicado: (2010)

Variation at FCGR2A and Functionally Related Genes Is Associated with the Response to Anti-TNF Therapy in Rheumatoid Arthritis
por: Avila-Pedretti, Gabriela, et al.
Publicado: (2015)

Features of the Synovium of Individuals at Risk of Developing Rheumatoid Arthritis: Implications for Understanding Preclinical Rheumatoid Arthritis
por: de Hair, MJH, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_650js1clefsafuo2ss4721qhlc