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Use of a Targeted Exome Next-Generation Sequencing Panel Offers Therapeutic Opportunity and Clinical Benefit in a Subset of Patients With Advanced Cancers

PURPOSE: Smaller hotspot-based next-generation sequencing (NGS) panels have emerged to support standard of care therapy for patients with cancer. When standard treatments fail, it is unknown whether additional testing using an expanded panel of genes provides any benefit. The purpose of this study w...

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Detalles Bibliográficos
Autores principales: Kopetz, Scott, Mills Shaw, Kenna R., Lee, J. Jack, Zhang, Jiexin, Litzenburger, Beate, Holla, Vijaykumar, Kinyua, Walter, Broaddus, Emily, Daniels, Molly S., Meric-Bernstam, Funda, Broaddus, Russell R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446317/
https://www.ncbi.nlm.nih.gov/pubmed/32914008
http://dx.doi.org/10.1200/PO.18.00213