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Impact of hyperglycemia and treatment with metformin on ligature-induced bone loss, bone repair and expression of bone metabolism transcription factors

This study evaluated the influence of type 2 diabetes mellitus on bone loss, bone repair and cytokine production in hyperglycemic rats, treated or not with metformin. The animals were distributed as follow: Non-Hyperglycemic (NH), Non Hyperglycemic with Ligature (NH-L), Treated Non Hyperglycemic (TN...

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Detalles Bibliográficos
Autores principales: Malta, Fernando Souza, Garcia, Roberto Puertas, Azarias, Josuel Siqueira, Ribeiro, Geysica Kauane Dos Reis, Miranda, Tamires Szemereske, Shibli, Jamil Awad, Bastos, Marta Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447028/
https://www.ncbi.nlm.nih.gov/pubmed/32841254
http://dx.doi.org/10.1371/journal.pone.0237660

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