Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program

BACKGROUND & AIMS: Given ongoing challenges in non-invasive non-alcoholic liver disease (NAFLD) diagnosis, we sought to validate an ALT-based NAFLD phenotype using measures readily available in electronic health records (EHRs) and population-based studies by leveraging the clinical and genetic d...

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Detalles Bibliográficos
Autores principales: Serper, Marina, Vujkovic, Marijana, Kaplan, David E., Carr, Rotonya M., Lee, Kyung Min, Shao, Qing, Miller, Donald R., Reaven, Peter D., Phillips, Lawrence S., O’Donnell, Christopher J., Meigs, James B., Wilson, Peter W. F., Vickers-Smith, Rachel, Kranzler, Henry R., Justice, Amy C., Gaziano, John M., Muralidhar, Sumitra, Pyarajan, Saiju, DuVall, Scott L., Assimes, Themistocles L., Lee, Jennifer S., Tsao, Philip S., Rader, Daniel J., Damrauer, Scott M., Lynch, Julie A., Saleheen, Danish, Voight, Benjamin F., Chang, Kyong-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447043/
https://www.ncbi.nlm.nih.gov/pubmed/32841307
http://dx.doi.org/10.1371/journal.pone.0237430

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