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Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya

INTRODUCTION: Human immunodeficiency virus (HIV) assisted partner services (aPS) has been recommended as a strategy to increase HIV case finding. We evaluated factors associated with poor linkage to HIV care among newly diagnosed HIV-positive individuals (index clients) and their partners after rece...

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Autores principales: Wamuti, Beatrice, Contesse, Marielle G., Maingi, Peter, Macharia, Paul, Abuna, Felix, Sambai, Betsy, Ng'ang'a, Anne, Spiegel, Hans, Richardson, Barbra, Cherutich, Peter, Bukusi, David, Farquhar, Carey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447121/
https://www.ncbi.nlm.nih.gov/pubmed/32815902
http://dx.doi.org/10.1097/OLQ.0000000000001222
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author Wamuti, Beatrice
Contesse, Marielle G.
Maingi, Peter
Macharia, Paul
Abuna, Felix
Sambai, Betsy
Ng'ang'a, Anne
Spiegel, Hans
Richardson, Barbra
Cherutich, Peter
Bukusi, David
Farquhar, Carey
author_facet Wamuti, Beatrice
Contesse, Marielle G.
Maingi, Peter
Macharia, Paul
Abuna, Felix
Sambai, Betsy
Ng'ang'a, Anne
Spiegel, Hans
Richardson, Barbra
Cherutich, Peter
Bukusi, David
Farquhar, Carey
author_sort Wamuti, Beatrice
collection PubMed
description INTRODUCTION: Human immunodeficiency virus (HIV) assisted partner services (aPS) has been recommended as a strategy to increase HIV case finding. We evaluated factors associated with poor linkage to HIV care among newly diagnosed HIV-positive individuals (index clients) and their partners after receiving aPS in Kenya. METHODS: In a cluster randomized trial conducted between 2013 and 2015, 9 facilities were randomized to immediate aPS (intervention). Linkage to care—defined as HIV clinic registration, and antiretroviral therapy (ART) initiation were self-reported. Antiretroviral therapy was only offered to those with CD4 less than 500 during this period. We estimated linkage to care and ART initiation separately for index clients and their partners using log-binomial generalized estimating equation models with exchangeable correlation structure and robust standard errors. RESULTS: Overall, 550 index clients and 621 sex partners enrolled, of whom 46% (284 of 621) were HIV-positive. Of the 284, 264 (93%) sex partners returned at 6 weeks: 120 newly diagnosed and 144 whom had known HIV-positive status. Among the 120 newly diagnosed, only 69% (83) linked to care at 6 weeks, whereas among the 18 known HIV-positive sex partners not already in care at baseline, 61% (11) linked. Newly diagnosed HIV-positive sex partners who were younger and single were less likely to link to care (P < 0.05 for all). CONCLUSION: Only two thirds of newly diagnosed, and known HIV-positive sex partners not in care linked to care after receiving aPS. The HIV aPS programs should optimize HIV care for newly diagnosed HIV-positive sex partners, especially those who are younger and single.
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spelling pubmed-74471212020-09-11 Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya Wamuti, Beatrice Contesse, Marielle G. Maingi, Peter Macharia, Paul Abuna, Felix Sambai, Betsy Ng'ang'a, Anne Spiegel, Hans Richardson, Barbra Cherutich, Peter Bukusi, David Farquhar, Carey Sex Transm Dis Original Studies INTRODUCTION: Human immunodeficiency virus (HIV) assisted partner services (aPS) has been recommended as a strategy to increase HIV case finding. We evaluated factors associated with poor linkage to HIV care among newly diagnosed HIV-positive individuals (index clients) and their partners after receiving aPS in Kenya. METHODS: In a cluster randomized trial conducted between 2013 and 2015, 9 facilities were randomized to immediate aPS (intervention). Linkage to care—defined as HIV clinic registration, and antiretroviral therapy (ART) initiation were self-reported. Antiretroviral therapy was only offered to those with CD4 less than 500 during this period. We estimated linkage to care and ART initiation separately for index clients and their partners using log-binomial generalized estimating equation models with exchangeable correlation structure and robust standard errors. RESULTS: Overall, 550 index clients and 621 sex partners enrolled, of whom 46% (284 of 621) were HIV-positive. Of the 284, 264 (93%) sex partners returned at 6 weeks: 120 newly diagnosed and 144 whom had known HIV-positive status. Among the 120 newly diagnosed, only 69% (83) linked to care at 6 weeks, whereas among the 18 known HIV-positive sex partners not already in care at baseline, 61% (11) linked. Newly diagnosed HIV-positive sex partners who were younger and single were less likely to link to care (P < 0.05 for all). CONCLUSION: Only two thirds of newly diagnosed, and known HIV-positive sex partners not in care linked to care after receiving aPS. The HIV aPS programs should optimize HIV care for newly diagnosed HIV-positive sex partners, especially those who are younger and single. Lippincott Williams & Wilkins 2020-09 2020-07-06 /pmc/articles/PMC7447121/ /pubmed/32815902 http://dx.doi.org/10.1097/OLQ.0000000000001222 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Sexually Transmitted Diseases Association. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Original Studies
Wamuti, Beatrice
Contesse, Marielle G.
Maingi, Peter
Macharia, Paul
Abuna, Felix
Sambai, Betsy
Ng'ang'a, Anne
Spiegel, Hans
Richardson, Barbra
Cherutich, Peter
Bukusi, David
Farquhar, Carey
Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya
title Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya
title_full Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya
title_fullStr Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya
title_full_unstemmed Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya
title_short Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya
title_sort factors associated with poor linkage to human immunodeficiency virus care among index clients and sex partners receiving human immunodeficiency virus assisted partner services in kenya
topic Original Studies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447121/
https://www.ncbi.nlm.nih.gov/pubmed/32815902
http://dx.doi.org/10.1097/OLQ.0000000000001222
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