Cargando…
Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya
INTRODUCTION: Human immunodeficiency virus (HIV) assisted partner services (aPS) has been recommended as a strategy to increase HIV case finding. We evaluated factors associated with poor linkage to HIV care among newly diagnosed HIV-positive individuals (index clients) and their partners after rece...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447121/ https://www.ncbi.nlm.nih.gov/pubmed/32815902 http://dx.doi.org/10.1097/OLQ.0000000000001222 |
_version_ | 1783574243195224064 |
---|---|
author | Wamuti, Beatrice Contesse, Marielle G. Maingi, Peter Macharia, Paul Abuna, Felix Sambai, Betsy Ng'ang'a, Anne Spiegel, Hans Richardson, Barbra Cherutich, Peter Bukusi, David Farquhar, Carey |
author_facet | Wamuti, Beatrice Contesse, Marielle G. Maingi, Peter Macharia, Paul Abuna, Felix Sambai, Betsy Ng'ang'a, Anne Spiegel, Hans Richardson, Barbra Cherutich, Peter Bukusi, David Farquhar, Carey |
author_sort | Wamuti, Beatrice |
collection | PubMed |
description | INTRODUCTION: Human immunodeficiency virus (HIV) assisted partner services (aPS) has been recommended as a strategy to increase HIV case finding. We evaluated factors associated with poor linkage to HIV care among newly diagnosed HIV-positive individuals (index clients) and their partners after receiving aPS in Kenya. METHODS: In a cluster randomized trial conducted between 2013 and 2015, 9 facilities were randomized to immediate aPS (intervention). Linkage to care—defined as HIV clinic registration, and antiretroviral therapy (ART) initiation were self-reported. Antiretroviral therapy was only offered to those with CD4 less than 500 during this period. We estimated linkage to care and ART initiation separately for index clients and their partners using log-binomial generalized estimating equation models with exchangeable correlation structure and robust standard errors. RESULTS: Overall, 550 index clients and 621 sex partners enrolled, of whom 46% (284 of 621) were HIV-positive. Of the 284, 264 (93%) sex partners returned at 6 weeks: 120 newly diagnosed and 144 whom had known HIV-positive status. Among the 120 newly diagnosed, only 69% (83) linked to care at 6 weeks, whereas among the 18 known HIV-positive sex partners not already in care at baseline, 61% (11) linked. Newly diagnosed HIV-positive sex partners who were younger and single were less likely to link to care (P < 0.05 for all). CONCLUSION: Only two thirds of newly diagnosed, and known HIV-positive sex partners not in care linked to care after receiving aPS. The HIV aPS programs should optimize HIV care for newly diagnosed HIV-positive sex partners, especially those who are younger and single. |
format | Online Article Text |
id | pubmed-7447121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-74471212020-09-11 Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya Wamuti, Beatrice Contesse, Marielle G. Maingi, Peter Macharia, Paul Abuna, Felix Sambai, Betsy Ng'ang'a, Anne Spiegel, Hans Richardson, Barbra Cherutich, Peter Bukusi, David Farquhar, Carey Sex Transm Dis Original Studies INTRODUCTION: Human immunodeficiency virus (HIV) assisted partner services (aPS) has been recommended as a strategy to increase HIV case finding. We evaluated factors associated with poor linkage to HIV care among newly diagnosed HIV-positive individuals (index clients) and their partners after receiving aPS in Kenya. METHODS: In a cluster randomized trial conducted between 2013 and 2015, 9 facilities were randomized to immediate aPS (intervention). Linkage to care—defined as HIV clinic registration, and antiretroviral therapy (ART) initiation were self-reported. Antiretroviral therapy was only offered to those with CD4 less than 500 during this period. We estimated linkage to care and ART initiation separately for index clients and their partners using log-binomial generalized estimating equation models with exchangeable correlation structure and robust standard errors. RESULTS: Overall, 550 index clients and 621 sex partners enrolled, of whom 46% (284 of 621) were HIV-positive. Of the 284, 264 (93%) sex partners returned at 6 weeks: 120 newly diagnosed and 144 whom had known HIV-positive status. Among the 120 newly diagnosed, only 69% (83) linked to care at 6 weeks, whereas among the 18 known HIV-positive sex partners not already in care at baseline, 61% (11) linked. Newly diagnosed HIV-positive sex partners who were younger and single were less likely to link to care (P < 0.05 for all). CONCLUSION: Only two thirds of newly diagnosed, and known HIV-positive sex partners not in care linked to care after receiving aPS. The HIV aPS programs should optimize HIV care for newly diagnosed HIV-positive sex partners, especially those who are younger and single. Lippincott Williams & Wilkins 2020-09 2020-07-06 /pmc/articles/PMC7447121/ /pubmed/32815902 http://dx.doi.org/10.1097/OLQ.0000000000001222 Text en Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Sexually Transmitted Diseases Association. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Original Studies Wamuti, Beatrice Contesse, Marielle G. Maingi, Peter Macharia, Paul Abuna, Felix Sambai, Betsy Ng'ang'a, Anne Spiegel, Hans Richardson, Barbra Cherutich, Peter Bukusi, David Farquhar, Carey Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya |
title | Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya |
title_full | Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya |
title_fullStr | Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya |
title_full_unstemmed | Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya |
title_short | Factors Associated With Poor Linkage to Human Immunodeficiency Virus Care Among Index Clients and Sex Partners Receiving Human Immunodeficiency Virus Assisted Partner Services in Kenya |
title_sort | factors associated with poor linkage to human immunodeficiency virus care among index clients and sex partners receiving human immunodeficiency virus assisted partner services in kenya |
topic | Original Studies |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447121/ https://www.ncbi.nlm.nih.gov/pubmed/32815902 http://dx.doi.org/10.1097/OLQ.0000000000001222 |
work_keys_str_mv | AT wamutibeatrice factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT contessemarielleg factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT maingipeter factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT machariapaul factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT abunafelix factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT sambaibetsy factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT ngangaanne factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT spiegelhans factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT richardsonbarbra factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT cherutichpeter factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT bukusidavid factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya AT farquharcarey factorsassociatedwithpoorlinkagetohumanimmunodeficiencyviruscareamongindexclientsandsexpartnersreceivinghumanimmunodeficiencyvirusassistedpartnerservicesinkenya |