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CaMKII controls neuromodulation via neuropeptide gene expression and axonal targeting of neuropeptide vesicles
Ca(2+)/calmodulin-dependent kinase II (CaMKII) regulates synaptic plasticity in multiple ways, supposedly including the secretion of neuromodulators like brain-derived neurotrophic factor (BDNF). Here, we show that neuromodulator secretion is indeed reduced in mouse α- and βCaMKII-deficient (αβCaMKI...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447270/ https://www.ncbi.nlm.nih.gov/pubmed/32776935 http://dx.doi.org/10.1371/journal.pbio.3000826 |