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Sebaceous Gland Carcinoma with Misleading Clinical Appearance: A Case Report of an Eyelid Lesion

Patient: Female, 53-year-old Final Diagnosis: Sebaceous gland carcinoma Symptoms: Mass in right lower lid Medication: — Clinical Procedure: Full-thickness wedge resection with frozen section control Specialty: Oncology • Ophthalmology • Pathology OBJECTIVE: Challenging differential diagnosis BACKGRO...

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Detalles Bibliográficos
Autores principales: Helmi, Hala A., Alsarhani, Waleed, Alkatan, Hind Manaa, Al-Rikabi, Ammar C., Al-Faky, Yasser H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447290/
https://www.ncbi.nlm.nih.gov/pubmed/32788569
http://dx.doi.org/10.12659/AJCR.925134
Descripción
Sumario:Patient: Female, 53-year-old Final Diagnosis: Sebaceous gland carcinoma Symptoms: Mass in right lower lid Medication: — Clinical Procedure: Full-thickness wedge resection with frozen section control Specialty: Oncology • Ophthalmology • Pathology OBJECTIVE: Challenging differential diagnosis BACKGROUND: Sebaceous gland carcinoma (SGC) is a rare malignant lesion that occurs on the eyelids. It is known to mimic other benign or malignant lesions in clinical presentation, such as a chalazion, basal cell carcinoma, and squamous cell carcinoma. The histopathological diagnosis is the mainstay for diagnosis and is often challenging. CASE REPORT: We describe a case of SGC in a 53-year-old woman who presented with a cauliflower-appearing lesion with pearly telangiectatic vessels and raised margins at the lower eyelid margin. Clinically, we suspected a diagnosis of basal cell carcinoma. Upon complete resection of the lesion, the final diagnosis was SGC based on the histopathological features and immunohistochemical staining characteristics of the tissue. CONCLUSIONS: Due to the possibility of SGC presenting similarly to other lesions, it is essential for ophthalmologists to have a high index of suspicion in its diagnosis. The early and accurate diagnosis of such lesions is important for appropriate management to prevent metastasis or recurrence related to advanced tumors.