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MicroRNA-145 promotes the apoptosis of leukemic stem cells and enhances drug-resistant K562/ADM cell sensitivity to adriamycin via the regulation of ABCE1

Leukemia is a type of cancer which originates in blood-forming tissues. MicroRNAs (miRNAs or miRs) have been shown to be involved leukemogenesis. In the present study, following the gain- and loss-function of miR-145 and ATP-binding cassette sub-family E member 1 (ABCE1) in K562 cells and K562 adria...

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Detalles Bibliográficos
Autores principales:	Wuxiao, Zhijun, Wang, Hua, Su, Qunhao, Zhou, Haiyan, Hu, Min, Tao, Shi, Xu, Lu, Chen, Yu, Hao, Xinbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447303/ https://www.ncbi.nlm.nih.gov/pubmed/32945355 http://dx.doi.org/10.3892/ijmm.2020.4675

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