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Overexpression of FcγRIIB regulates downstream protein phosphorylation and suppresses B cell activation to ameliorate systemic lupus erythematosus

The present study aimed to examine the effects of FcγRIIB on systemic lupus erythematosus (SLE) and to investigate the underlying mechanisms. For this purpose, lentiviral vector carrying the membrane-bound type FcγRIIB gene (mFcγRIIB lentivirus) and soluble FcγRIIB (sFcγRIIB) protein were used to tr...

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Detalles Bibliográficos
Autores principales:	Sheng, Linlin, Cao, Xiuqin, Chi, Shuhong, Wu, Jing, Xing, Huihui, Liu, Huiyu, Yang, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447306/ https://www.ncbi.nlm.nih.gov/pubmed/32945349 http://dx.doi.org/10.3892/ijmm.2020.4698

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