Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon

Necrobiotic pulmonary nodules are an exceptionally rare extraintestinal manifestation of inflammatory bowel disease. Recognition is imperative because it may mimic other autoimmune pathologies such as granulomatosis with polyangiitis or sarcoidosis. We describe a 19-year-old man with a known history...

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Autores principales: Mukherjee, Samiran, Harne, Prateek, Mirchia, Kanish, Sharma, Anuj, Manocha, Divey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447367/
https://www.ncbi.nlm.nih.gov/pubmed/32903944
http://dx.doi.org/10.14309/crj.0000000000000438
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author Mukherjee, Samiran
Harne, Prateek
Mirchia, Kanish
Sharma, Anuj
Manocha, Divey
author_facet Mukherjee, Samiran
Harne, Prateek
Mirchia, Kanish
Sharma, Anuj
Manocha, Divey
author_sort Mukherjee, Samiran
collection PubMed
description Necrobiotic pulmonary nodules are an exceptionally rare extraintestinal manifestation of inflammatory bowel disease. Recognition is imperative because it may mimic other autoimmune pathologies such as granulomatosis with polyangiitis or sarcoidosis. We describe a 19-year-old man with a known history of ulcerative colitis who was found to possess bilateral pulmonary nodules on computed tomography imaging. Investigations that included an extensive autoimmune and infectious workup were inconclusive. Biopsy of the nodules revealed fibrinous exudate and palisading histiocytes that confirmed the diagnosis. He was started on prednisone therapy. A follow-up computed tomography a month later revealed near complete resolution.
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spelling pubmed-74473672020-09-04 Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon Mukherjee, Samiran Harne, Prateek Mirchia, Kanish Sharma, Anuj Manocha, Divey ACG Case Rep J Case Report Necrobiotic pulmonary nodules are an exceptionally rare extraintestinal manifestation of inflammatory bowel disease. Recognition is imperative because it may mimic other autoimmune pathologies such as granulomatosis with polyangiitis or sarcoidosis. We describe a 19-year-old man with a known history of ulcerative colitis who was found to possess bilateral pulmonary nodules on computed tomography imaging. Investigations that included an extensive autoimmune and infectious workup were inconclusive. Biopsy of the nodules revealed fibrinous exudate and palisading histiocytes that confirmed the diagnosis. He was started on prednisone therapy. A follow-up computed tomography a month later revealed near complete resolution. Wolters Kluwer 2020-08-20 /pmc/articles/PMC7447367/ /pubmed/32903944 http://dx.doi.org/10.14309/crj.0000000000000438 Text en © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work, provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Mukherjee, Samiran
Harne, Prateek
Mirchia, Kanish
Sharma, Anuj
Manocha, Divey
Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon
title Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon
title_full Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon
title_fullStr Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon
title_full_unstemmed Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon
title_short Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a “Crohnic” Phenomenon
title_sort necrobiotic pulmonary nodules in ulcerative colitis: not just a “crohnic” phenomenon
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447367/
https://www.ncbi.nlm.nih.gov/pubmed/32903944
http://dx.doi.org/10.14309/crj.0000000000000438
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