Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

Approximately 30% of older adults exhibit the neuropathological features of Alzheimer’s disease without signs of cognitive impairment. Yet, little is known about the genetic factors that allow these potentially resilient individuals to remain cognitively unimpaired in the face of substantial neuropa...

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Detalles Bibliográficos
Autores principales: Dumitrescu, Logan, Mahoney, Emily R, Mukherjee, Shubhabrata, Lee, Michael L, Bush, William S, Engelman, Corinne D, Lu, Qiongshi, Fardo, David W, Trittschuh, Emily H, Mez, Jesse, Kaczorowski, Catherine, Hernandez Saucedo, Hector, Widaman, Keith F, Buckley, Rachel, Properzi, Michael, Mormino, Elizabeth, Yang, Hyun-Sik, Harrison, Tessa, Hedden, Trey, Nho, Kwangsik, Andrews, Shea J, Tommet, Doug, Hadad, Niran, Sanders, R Elizabeth, Ruderfer, Douglas M, Gifford, Katherine A, Moore, Annah M, Cambronero, Francis, Zhong, Xiaoyuan, Raghavan, Neha S, Vardarajan, Badri, Pericak-Vance, Margaret A, Farrer, Lindsay A, Wang, Li-San, Cruchaga, Carlos, Schellenberg, Gerard, Cox, Nancy J, Haines, Jonathan L, Keene, C Dirk, Saykin, Andrew J, Larson, Eric B, Sperling, Reisa A, Mayeux, Richard, Bennett, David A, Schneider, Julie A, Crane, Paul K, Jefferson, Angela L, Hohman, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447518/
https://www.ncbi.nlm.nih.gov/pubmed/32844198
http://dx.doi.org/10.1093/brain/awaa209

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