Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model

The glymphatic system, that is aquaporin 4 (AQP4) facilitated exchange of CSF with interstitial fluid (ISF), may provide a clearance pathway for protein species such as amyloid-β and tau, which accumulate in the brain in Alzheimer’s disease. Further, tau protein transference via the extracellular sp...

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Detalles Bibliográficos
Autores principales: Harrison, Ian F, Ismail, Ozama, Machhada, Asif, Colgan, Niall, Ohene, Yolanda, Nahavandi, Payam, Ahmed, Zeshan, Fisher, Alice, Meftah, Soraya, Murray, Tracey K, Ottersen, Ole P, Nagelhus, Erlend A, O’Neill, Michael J, Wells, Jack A, Lythgoe, Mark F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447521/
https://www.ncbi.nlm.nih.gov/pubmed/32705145
http://dx.doi.org/10.1093/brain/awaa179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447521/
https://www.ncbi.nlm.nih.gov/pubmed/32705145
http://dx.doi.org/10.1093/brain/awaa179

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