Serum 20S proteasome levels are associated with disease activity in MPO-ANCA-associated microscopic polyangiitis

BACKGROUND: Proteasomes are found in both the cell nucleus and cytoplasm and play a major role in the ubiquitin-dependent and -independent non-lysosomal pathways of intracellular protein degradation. Proteasomes are also involved in the turnover of various regulatory proteins, antigen processing, ce...

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Detalles Bibliográficos
Autores principales: Maruyama, Hiroshi, Hirayama, Kouichi, Yamashita, Marina, Ohgi, Kentaro, Tsujimoto, Ryuji, Takayasu, Mamiko, Shimohata, Homare, Kobayashi, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447580/
https://www.ncbi.nlm.nih.gov/pubmed/32864569
http://dx.doi.org/10.1186/s41927-020-00137-4

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