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The effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial

OBJECTIVES: To investigate the effect of continuous infusion of the potential endothelial cytoprotective agent prostacyclin (Iloprost) 1 ng/kg/min vs. placebo for 72 hours on pulmonary endotheliopathy in mechanically ventilated COVID-19 patients. TRIAL DESIGN: A multicenter, randomized (1:1, active:...

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Detalles Bibliográficos
Autores principales:	Johansson, Pär Ingemar, Bestle, Morten, Søe-Jensen, Peter, Kristiansen, Klaus Tjelle, Stensballe, Jakob, Clausen, Niels Erikstrup, Perner, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447606/ https://www.ncbi.nlm.nih.gov/pubmed/32847626 http://dx.doi.org/10.1186/s13063-020-04696-2

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