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Fenpropathrin induces degeneration of dopaminergic neurons via disruption of the mitochondrial quality control system

The synthetic pyrethroid derivative, fenpropathrin, is a widely used insecticide. However, a variety of toxic effects in mammals have been reported. In particular, fenpropathrin induces degeneration of dopaminergic neurons and parkinsonism. However, the mechanism of fenpropathrin-induced parkinsonis...

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Detalles Bibliográficos
Autores principales: Jiao, Zhigang, Wu, Yixuan, Qu, Shaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447795/
https://www.ncbi.nlm.nih.gov/pubmed/32884840
http://dx.doi.org/10.1038/s41420-020-00313-y