DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans

Membraneless organelles are sites for RNA biology including small non-coding RNA (ncRNA) mediated gene silencing. How small ncRNAs utilise phase separated environments for their function is unclear. We investigated how the PIWI-interacting RNA (piRNA) pathway engages with the membraneless organelle...

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Detalles Bibliográficos
Autores principales: Suen, Kin Man, Braukmann, Fabian, Butler, Richard, Bensaddek, Dalila, Akay, Alper, Lin, Chi-Chuan, Milonaitytė, Dovilė, Doshi, Neel, Sapetschnig, Alexandra, Lamond, Angus, Ladbury, John Edward, Miska, Eric Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447803/
https://www.ncbi.nlm.nih.gov/pubmed/32843637
http://dx.doi.org/10.1038/s41467-020-18089-1

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