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Inferring clonal composition from multiple tumor biopsies

Knowledge about the clonal evolution of a tumor can help to interpret the function of its genetic alterations by identifying initiating events and events that contribute to the selective advantage of proliferative, metastatic, and drug-resistant subclones. Clonal evolution can be reconstructed from...

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Detalles Bibliográficos
Autores principales: Manica, Matteo, Kim, Hyunjae Ryan, Mathis, Roland, Chouvarine, Philippe, Rutishauser, Dorothea, De Vargas Roditi, Laura, Szalai, Bence, Wagner, Ulrich, Oehl, Kathrin, Saba, Karim, Pati, Arati, Saez-Rodriguez, Julio, Roy, Angshumoy, Parsons, Donald W., Wild, Peter J., Martínez, María Rodríguez, Sumazin, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447821/
https://www.ncbi.nlm.nih.gov/pubmed/32843649
http://dx.doi.org/10.1038/s41540-020-00147-5

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