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Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia

Congenital Rubella Syndrome (CRS) consists of hearing impairment, ophthalmology abnormalities, and congenital heart disease in children, resulting from rubella infection during pregnancy. Rubella vaccine has been implemented as national immunization program in Indonesia since 2017, and needed to be...

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Autores principales: Rosalina, Elsa, Purnami, Nyilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447925/
https://www.ncbi.nlm.nih.gov/pubmed/32874477
http://dx.doi.org/10.4081/idr.2020.8762
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author Rosalina, Elsa
Purnami, Nyilo
author_facet Rosalina, Elsa
Purnami, Nyilo
author_sort Rosalina, Elsa
collection PubMed
description Congenital Rubella Syndrome (CRS) consists of hearing impairment, ophthalmology abnormalities, and congenital heart disease in children, resulting from rubella infection during pregnancy. Rubella vaccine has been implemented as national immunization program in Indonesia since 2017, and needed to be evaluated. This study aimed to report the CRS patients’ profile of Audiology Outpatient Clinic in Surabaya. A descriptive study from patient’s medical record was conducted in Dr. Soetomo Hospital Surabaya from January 2016 to December 2017. CRS was categorized using World Health Organization classification. Suspected infants with CRS burden were assessed by Otoacoustic Emission and rubella antibody test. Ninety five infants suspected with CRS classified as laboratory- confirmed CRS (58.95%), clinically confirmed CRS (15.79%), and discarded CRS (25.26%). Clinical manifestations included combination of congenital heart disease and hearing impairment (17.89%), congenital heart disease, ophthalmology abnormalities, and hearing impairment (16.84%), and hearing impairment and ophthalmology abnormalities (13.68%). The data show a high burden of CRS in Surabaya. These implies the urgent need for national rubella immunization program.
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spelling pubmed-74479252020-08-31 Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia Rosalina, Elsa Purnami, Nyilo Infect Dis Rep Article Congenital Rubella Syndrome (CRS) consists of hearing impairment, ophthalmology abnormalities, and congenital heart disease in children, resulting from rubella infection during pregnancy. Rubella vaccine has been implemented as national immunization program in Indonesia since 2017, and needed to be evaluated. This study aimed to report the CRS patients’ profile of Audiology Outpatient Clinic in Surabaya. A descriptive study from patient’s medical record was conducted in Dr. Soetomo Hospital Surabaya from January 2016 to December 2017. CRS was categorized using World Health Organization classification. Suspected infants with CRS burden were assessed by Otoacoustic Emission and rubella antibody test. Ninety five infants suspected with CRS classified as laboratory- confirmed CRS (58.95%), clinically confirmed CRS (15.79%), and discarded CRS (25.26%). Clinical manifestations included combination of congenital heart disease and hearing impairment (17.89%), congenital heart disease, ophthalmology abnormalities, and hearing impairment (16.84%), and hearing impairment and ophthalmology abnormalities (13.68%). The data show a high burden of CRS in Surabaya. These implies the urgent need for national rubella immunization program. PAGEPress Publications, Pavia, Italy 2020-07-06 /pmc/articles/PMC7447925/ /pubmed/32874477 http://dx.doi.org/10.4081/idr.2020.8762 Text en ©Copyright: the Author(s) http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Rosalina, Elsa
Purnami, Nyilo
Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia
title Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia
title_full Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia
title_fullStr Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia
title_full_unstemmed Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia
title_short Congenital Rubella Syndrome profile of audiology outpatient clinic in Surabaya, Indonesia
title_sort congenital rubella syndrome profile of audiology outpatient clinic in surabaya, indonesia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447925/
https://www.ncbi.nlm.nih.gov/pubmed/32874477
http://dx.doi.org/10.4081/idr.2020.8762
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