Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

BACKGROUND: Cross-sectional imaging regularly results in incidental discovery of adrenal tumours, requiring exclusion of adrenocortical carcinoma (ACC). However, differentiation is hampered by poor specificity of imaging characteristics. We aimed to validate a urine steroid metabolomics approach, us...

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Detalles Bibliográficos
Autores principales: Bancos, Irina, Taylor, Angela E, Chortis, Vasileios, Sitch, Alice J, Jenkinson, Carl, Davidge-Pitts, Caroline J, Lang, Katharina, Tsagarakis, Stylianos, Macech, Magdalena, Riester, Anna, Deutschbein, Timo, Pupovac, Ivana D, Kienitz, Tina, Prete, Alessandro, Papathomas, Thomas G, Gilligan, Lorna C, Bancos, Cristian, Reimondo, Giuseppe, Haissaguerre, Magalie, Marina, Ljiljana, Grytaas, Marianne A, Sajwani, Ahmed, Langton, Katharina, Ivison, Hannah E, Shackleton, Cedric H L, Erickson, Dana, Asia, Miriam, Palimeri, Sotiria, Kondracka, Agnieszka, Spyroglou, Ariadni, Ronchi, Cristina L, Simunov, Bojana, Delivanis, Danae A, Sutcliffe, Robert P, Tsirou, Ioanna, Bednarczuk, Tomasz, Reincke, Martin, Burger-Stritt, Stephanie, Feelders, Richard A, Canu, Letizia, Haak, Harm R, Eisenhofer, Graeme, Dennedy, M Conall, Ueland, Grethe A, Ivovic, Miomira, Tabarin, Antoine, Terzolo, Massimo, Quinkler, Marcus, Kastelan, Darko, Fassnacht, Martin, Beuschlein, Felix, Ambroziak, Urszula, Vassiliadi, Dimitra A, O'Reilly, Michael W, Young, William F, Biehl, Michael, Deeks, Jonathan J, Arlt, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Lancet, Diabetes & Endocrinology 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447976/
https://www.ncbi.nlm.nih.gov/pubmed/32711725
http://dx.doi.org/10.1016/S2213-8587(20)30218-7

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