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The ASC-1 Complex Disassembles Collided Ribosomes

Translating ribosomes that slow excessively incur collisions with trailing ribosomes. Persistent collisions are detected by ZNF598, a ubiquitin ligase that ubiquitinates sites on the ribosomal 40S subunit to initiate pathways of mRNA and protein quality control. The collided ribosome complex must be...

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Detalles Bibliográficos
Autores principales:	Juszkiewicz, Szymon, Speldewinde, Shaun H., Wan, Li, Svejstrup, Jesper Q., Hegde, Ramanujan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447978/ https://www.ncbi.nlm.nih.gov/pubmed/32579943 http://dx.doi.org/10.1016/j.molcel.2020.06.006

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