The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates

Meiotic recombination proceeds via binding of RPA, RAD51, and DMC1 to single-stranded DNA (ssDNA) substrates created after formation of programmed DNA double-strand breaks. Here we report high-resolution in vivo maps of RPA and RAD51 in meiosis, mapping their binding locations and lifespans to indiv...

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Detalles Bibliográficos
Autores principales: Hinch, Anjali Gupta, Becker, Philipp W., Li, Tao, Moralli, Daniela, Zhang, Gang, Bycroft, Clare, Green, Catherine, Keeney, Scott, Shi, Qinghua, Davies, Benjamin, Donnelly, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447979/
https://www.ncbi.nlm.nih.gov/pubmed/32610038
http://dx.doi.org/10.1016/j.molcel.2020.06.015

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