Cargando…
Safety and efficacy of Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699 as a feed additive for all animal species
Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699 when used as a si...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448012/ https://www.ncbi.nlm.nih.gov/pubmed/32874291 http://dx.doi.org/10.2903/j.efsa.2020.6082 |
_version_ | 1783574412427001856 |
---|---|
author | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kos Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Prieto Maradona, Miguel Saarela, Maria Pettenati, Elisa Brozzi, Rosella |
author_facet | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kos Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Prieto Maradona, Miguel Saarela, Maria Pettenati, Elisa Brozzi, Rosella |
collection | PubMed |
description | Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699 when used as a silage additive in forage for all animal species. The additive is the result from the fermentation of milk‐based broth with L. rhamnosus CNCM I‐3698 and L. farciminis CNCM I‐3699. It is intended to be used in easy and moderately difficult to ensile materials at a minimum proposed application rate of 2.5 × 10(7) and maximum 8 × 10(7) VFU/kg complete feed for all animal species. The data provided do not allow a full characterisation of the additive, and therefore, uncertainty remains on the nature of the product in terms of viability, on the ratio between the active agents and on the shelf‐life of the additive. Both strains fulfil the requirements of the Qualified Presumption of Safety (QPS) approach to the assessment of safety and consequently, are presumed safe for the target animals, consumers of products from animals receiving the additive and the environment. The additive should be considered a respiratory sensitiser. In the absence of data, no conclusions can be drawn on the irritancy of the additive to skin and eyes or on its dermal sensitisation potential. No conclusions can be drawn on the efficacy of the additive to improve the ensiling process of easy and moderately difficult to ensile materials. |
format | Online Article Text |
id | pubmed-7448012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-74480122020-08-31 Safety and efficacy of Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699 as a feed additive for all animal species Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kos Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Prieto Maradona, Miguel Saarela, Maria Pettenati, Elisa Brozzi, Rosella EFSA J Scientific Opinion Following a request from the European Commission, the EFSA Panel on Additives and products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699 when used as a silage additive in forage for all animal species. The additive is the result from the fermentation of milk‐based broth with L. rhamnosus CNCM I‐3698 and L. farciminis CNCM I‐3699. It is intended to be used in easy and moderately difficult to ensile materials at a minimum proposed application rate of 2.5 × 10(7) and maximum 8 × 10(7) VFU/kg complete feed for all animal species. The data provided do not allow a full characterisation of the additive, and therefore, uncertainty remains on the nature of the product in terms of viability, on the ratio between the active agents and on the shelf‐life of the additive. Both strains fulfil the requirements of the Qualified Presumption of Safety (QPS) approach to the assessment of safety and consequently, are presumed safe for the target animals, consumers of products from animals receiving the additive and the environment. The additive should be considered a respiratory sensitiser. In the absence of data, no conclusions can be drawn on the irritancy of the additive to skin and eyes or on its dermal sensitisation potential. No conclusions can be drawn on the efficacy of the additive to improve the ensiling process of easy and moderately difficult to ensile materials. John Wiley and Sons Inc. 2020-04-30 /pmc/articles/PMC7448012/ /pubmed/32874291 http://dx.doi.org/10.2903/j.efsa.2020.6082 Text en © 2020 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kos Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Cocconcelli, Pier Sandro Glandorf, Boet Prieto Maradona, Miguel Saarela, Maria Pettenati, Elisa Brozzi, Rosella Safety and efficacy of Lactobacillus rhamnosus CNCM I‐3698 and Lactobacillus farciminis CNCM I‐3699 as a feed additive for all animal species |
title | Safety and efficacy of Lactobacillus rhamnosus
CNCM I‐3698 and Lactobacillus farciminis
CNCM I‐3699 as a feed additive for all animal species |
title_full | Safety and efficacy of Lactobacillus rhamnosus
CNCM I‐3698 and Lactobacillus farciminis
CNCM I‐3699 as a feed additive for all animal species |
title_fullStr | Safety and efficacy of Lactobacillus rhamnosus
CNCM I‐3698 and Lactobacillus farciminis
CNCM I‐3699 as a feed additive for all animal species |
title_full_unstemmed | Safety and efficacy of Lactobacillus rhamnosus
CNCM I‐3698 and Lactobacillus farciminis
CNCM I‐3699 as a feed additive for all animal species |
title_short | Safety and efficacy of Lactobacillus rhamnosus
CNCM I‐3698 and Lactobacillus farciminis
CNCM I‐3699 as a feed additive for all animal species |
title_sort | safety and efficacy of lactobacillus rhamnosus
cncm i‐3698 and lactobacillus farciminis
cncm i‐3699 as a feed additive for all animal species |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448012/ https://www.ncbi.nlm.nih.gov/pubmed/32874291 http://dx.doi.org/10.2903/j.efsa.2020.6082 |
work_keys_str_mv | AT safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT bampidisvasileios safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT azimontigiovanna safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT bastosmariadelourdes safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT christensenhenrik safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT dusemundbirgit safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT kosdurjavamojca safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT koubamaryline safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT lopezalonsomarta safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT lopezpuentesecundino safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT marconfrancesca safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT mayobaltasar safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT pechovaalena safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT petkovamariana safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT ramosfernando safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT sanzyolanda safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT villarobertoedoardo safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT woutersenruud safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT cocconcellipiersandro safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT glandorfboet safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT prietomaradonamiguel safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT saarelamaria safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT pettenatielisa safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies AT brozzirosella safetyandefficacyoflactobacillusrhamnosuscncmi3698andlactobacillusfarciminiscncmi3699asafeedadditiveforallanimalspecies |