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Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species

Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 8...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Kos Durjava, Mojca, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Herman, Lieve, Glandorf, Boet, Saarela, Maria, Galobart, Jaume, Holczknecht, Orsolya, Manini, Paola, Pettenati, Elisa, Tarrés Call, Jordi, Pizzo, Fabiola, Anguita, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448065/
https://www.ncbi.nlm.nih.gov/pubmed/32874293
http://dx.doi.org/10.2903/j.efsa.2020.6085
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kos Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Herman, Lieve
Glandorf, Boet
Saarela, Maria
Galobart, Jaume
Holczknecht, Orsolya
Manini, Paola
Pettenati, Elisa
Tarrés Call, Jordi
Pizzo, Fabiola
Anguita, Montserrat
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kos Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Herman, Lieve
Glandorf, Boet
Saarela, Maria
Galobart, Jaume
Holczknecht, Orsolya
Manini, Paola
Pettenati, Elisa
Tarrés Call, Jordi
Pizzo, Fabiola
Anguita, Montserrat
collection PubMed
description Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 80188 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is not genetically modified. Viable cells of the production strain were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. Monosodium l‐glutamate monohydrate produced using C. glutamicum KCCM 80188 is considered safe for the target species, for the consumer and for the environment. Monosodium l‐glutamate monohydrated produced by C. glutamicum KCCM 80188 is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed.
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spelling pubmed-74480652020-08-31 Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kos Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Herman, Lieve Glandorf, Boet Saarela, Maria Galobart, Jaume Holczknecht, Orsolya Manini, Paola Pettenati, Elisa Tarrés Call, Jordi Pizzo, Fabiola Anguita, Montserrat EFSA J Scientific Opinion Following a request from the European Commission, the Panel on Additives and Products or substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of monosodium l‐glutamate monohydrate produced by fermentation using Corynebacterium glutamicum KCCM 80188 when used as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is not genetically modified. Viable cells of the production strain were not detected in the final additive. The additive does not give rise to any safety concern regarding the production strain. Monosodium l‐glutamate monohydrate produced using C. glutamicum KCCM 80188 is considered safe for the target species, for the consumer and for the environment. Monosodium l‐glutamate monohydrated produced by C. glutamicum KCCM 80188 is considered not toxic by inhalation, not irritant to skin or eyes and not a dermal sensitiser. The FEEDAP Panel expressed reservations on the use of the additive in water for drinking due to concerns on its impact on the hygienic conditions of the water. The Panel concluded that the additive is efficacious to contribute to the flavour of feed. John Wiley and Sons Inc. 2020-04-28 /pmc/articles/PMC7448065/ /pubmed/32874293 http://dx.doi.org/10.2903/j.efsa.2020.6085 Text en © 2020 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kos Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Herman, Lieve
Glandorf, Boet
Saarela, Maria
Galobart, Jaume
Holczknecht, Orsolya
Manini, Paola
Pettenati, Elisa
Tarrés Call, Jordi
Pizzo, Fabiola
Anguita, Montserrat
Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species
title Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species
title_full Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species
title_fullStr Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species
title_full_unstemmed Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species
title_short Safety and efficacy of monosodium l‐glutamate monohydrate produced by Corynebacterium glutamicum KCCM 80188 as a feed additive for all animal species
title_sort safety and efficacy of monosodium l‐glutamate monohydrate produced by corynebacterium glutamicum kccm 80188 as a feed additive for all animal species
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448065/
https://www.ncbi.nlm.nih.gov/pubmed/32874293
http://dx.doi.org/10.2903/j.efsa.2020.6085
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