CSF chitinases before and after symptom onset in amyotrophic lateral sclerosis

OBJECTIVE: To evaluate the CSF levels of chitinase proteins during the presymptomatic and early symptomatic phases of amyotrophic lateral sclerosis (ALS). METHODS: CSF samples were obtained from 16 controls, 55 individuals at‐risk for ALS (including 18 carrying a mutation in C9ORF72, 33 in SOD1), 12...

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Detalles Bibliográficos
Autores principales: Gray, Elizabeth, Thompson, Alexander G., Wuu, Joanne, Pelt, Joe, Talbot, Kevin, Benatar, Michael, Turner, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448184/
https://www.ncbi.nlm.nih.gov/pubmed/32666680
http://dx.doi.org/10.1002/acn3.51114

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