Cargando…

Efflux Pump Antibiotic Binding Site Mutations Are Associated with Azithromycin Nonsusceptibility in Clinical Neisseria gonorrhoeae Isolates

Detalles Bibliográficos
Autores principales:	Ma, Kevin C., Mortimer, Tatum D., Grad, Yonatan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448274/ https://www.ncbi.nlm.nih.gov/pubmed/32843551 http://dx.doi.org/10.1128/mBio.01509-20

Ejemplares similares

Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae
por: Wadsworth, Crista B., et al.
Publicado: (2018)

Genomic Epidemiology of Azithromycin-Nonsusceptible Neisseria gonorrhoeae, Argentina, 2005–2019
por: Gianecini, Ricardo Ariel, et al.
Publicado: (2021)

A genomic perspective on the near-term impact of doxycycline post-exposure prophylaxis on Neisseria gonorrhoeae antimicrobial resistance
por: Mortimer, Tatum D., et al.
Publicado: (2023)

Loci for prediction of penicillin and tetracycline susceptibility in Neisseria gonorrhoeae: a genome-wide association study
por: Mortimer, Tatum D, et al.
Publicado: (2022)

RNA polymerase mutations cause cephalosporin resistance in clinical Neisseria gonorrhoeae isolates
por: Palace, Samantha G, et al.
Publicado: (2020)

Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae
por: Ma, Kevin C., et al.
Publicado: (2020)

Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae
por: Ma, Kevin C., et al.
Publicado: (2020)

Emergence and evolution of antimicrobial resistance genes and mutations in Neisseria gonorrhoeae
por: Yahara, Koji, et al.
Publicado: (2021)

Neisseria gonorrhoeae diagnostic escape from a gyrA-based test for ciprofloxacin susceptibility and the effect on zoliflodacin resistance: a bacterial genetics and experimental evolution study
por: Rubin, Daniel H F, et al.
Publicado: (2023)

WGS to predict antibiotic MICs for Neisseria gonorrhoeae
por: Eyre, David W., et al.
Publicado: (2017)

Self-Inhibitory Peptides Targeting the Neisseria gonorrhoeae MtrCDE Efflux Pump Increase Antibiotic Susceptibility
por: Evert, Benjamin J., et al.
Publicado: (2022)

Interactions between Loci Contributing to Antimicrobial Resistance and Virulence in Neisseria gonorrhoeae
por: Mortimer, Tatum D.
Publicado: (2022)

The Distribution and Spread of Susceptible and Resistant Neisseria gonorrhoeae Across Demographic Groups in a Major Metropolitan Center
por: Mortimer, Tatum D, et al.
Publicado: (2020)

Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump
por: Bolla, Jani Reddy, et al.
Publicado: (2014)

Mosaic Drug Efflux Gene Sequences from Commensal Neisseria Can Lead to Low-Level Azithromycin Resistance Expressed by Neisseria gonorrhoeae Clinical Isolates
por: Shafer, William M.
Publicado: (2018)

The MtrCDE Efflux Pump Contributes to Survival of Neisseria gonorrhoeae From Human Neutrophils and Their Antimicrobial Components
por: Handing, Jonathan W., et al.
Publicado: (2018)

1440. The Genetic Basis for a Neisseria gonorrhoeae Clinical Isolate That Contains mtrR(-79) Mutation But Is Highly Susceptible to Antibiotics Effluxed by the Mtr Pump System
por: Huang, Jianzhong, et al.
Publicado: (2020)

Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE
por: Tamburrino, Giulia, et al.
Publicado: (2017)

Emerging azithromycin-resistance among the Neisseria gonorrhoeae strains isolated in Hungary
por: Brunner, Alexandra, et al.
Publicado: (2016)

Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA
por: Papp, John R., et al.
Publicado: (2017)

Markedly decreasing azithromycin susceptibility of Neisseria gonorrhoeae, Germany, 2014 to 2021
por: Selb, Regina, et al.
Publicado: (2021)

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch
por: Sánchez-Busó, Leonor, et al.
Publicado: (2021)

Assessment of Antibiotic Resistance and Efflux Pump Gene Expression in Neisseria Gonorrhoeae Isolates from South Africa by Quantitative Real-Time PCR and Regression Analysis
por: Mitchev, Nireshni, et al.
Publicado: (2022)

Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada
por: Martin, I., et al.
Publicado: (2016)

Could Dampening Expression of the Neisseria gonorrhoeae mtrCDE-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?
por: Chen, Shaochun, et al.
Publicado: (2019)

Draft Genome Sequences of Three Penicillin-Resistant Neisseria gonorrhoeae Strains Isolated in Cincinnati, Ohio, in 1994
por: Murphy, Thomas C., et al.
Publicado: (2021)

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus
por: Rouquette-Loughlin, Corinne E., et al.
Publicado: (2018)

Genomic analyses of Neisseria gonorrhoeae reveal an association of the gonococcal genetic island with antimicrobial resistance
por: Harrison, Odile B., et al.
Publicado: (2016)

Neisseria gonorrhoeae
por: Ehrhard, Ingrid
Publicado: (2009)

Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018
por: Eyre, David W, et al.
Publicado: (2018)

Using rapid point-of-care tests to inform antibiotic choice to mitigate drug resistance in gonorrhoea
por: Vegvari, Carolin, et al.
Publicado: (2020)

Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017
por: Terkelsen, David, et al.
Publicado: (2017)

Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance, but high azithromycin resistance
por: Buder, Susanne, et al.
Publicado: (2018)

Fourteen Draft Genome Sequences for the First Reported Cases of Azithromycin-Resistant Neisseria gonorrhoeae in Ireland
por: Mac Aogáin, Micheál, et al.
Publicado: (2017)

Azithromycin Susceptibility Testing and Molecular Investigation of Neisseria gonorrhoeae Isolates Collected in Russia, 2020–2021
por: Kandinov, Ilya, et al.
Publicado: (2023)

Emergence of Azithromycin-Resistant Neisseria gonorrhoeae Isolates Belonging to the NG-MAST Genogroup 12302 in Russia
por: Kandinov, Ilya, et al.
Publicado: (2023)

Dueling Regulatory Properties of a Transcriptional Activator (MtrA) and Repressor (MtrR) That Control Efflux Pump Gene Expression in Neisseria gonorrhoeae
por: Zalucki, Yaramah M., et al.
Publicado: (2012)

Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon
por: Rouquette-Loughlin, Corinne E., et al.
Publicado: (2017)

Antibiotic Resistance in Neisseria gonorrhoeae: Challenges in Research and Treatment
por: Shaskolskiy, Boris, et al.
Publicado: (2022)

Extensively drug-resistant (XDR) Neisseria gonorrhoeae causing possible gonorrhoea treatment failure with ceftriaxone plus azithromycin in Austria, April 2022
por: Pleininger, Sonja, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mbhuj488ltrba068vm91qnif5f