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Unstructured regions of large enzymatic complexes control the availability of metabolites with signaling functions
ABSTRACT: Metabolites produced via traditional biochemical processes affect intracellular communication, inflammation, and malignancy. Unexpectedly, acetyl-CoA, α-ketoglutarate and palmitic acid, which are chemical species of reactions catalyzed by highly abundant, gigantic enzymatic complexes, dubb...
Autores principales: | Skalidis, Ioannis, Tüting, Christian, Kastritis, Panagiotis L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448341/ https://www.ncbi.nlm.nih.gov/pubmed/32843078 http://dx.doi.org/10.1186/s12964-020-00631-9 |
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