Cargando…
Kevetrin induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells
Tumor protein p53 is a key regulator of several cellular pathways, including DNA repair, cell cycle and angiogenesis. Kevetrin exhibits p53-dependent as well as-independent activity in solid tumors, while its effects on leukemic cells remain unknown. The aim of the present study was to analyze the r...
Autores principales: | Napolitano, Roberta, De Matteis, Serena, Carloni, Silvia, Bruno, Samantha, Abbati, Giulia, Capelli, Laura, Ghetti, Martina, Bochicchio, Maria Teresa, Liverani, Chiara, Mercatali, Laura, Calistri, Daniele, Cuneo, Antonio, Menon, Krishna, Musuraca, Gerardo, Martinelli, Giovanni, Simonetti, Giorgia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448420/ https://www.ncbi.nlm.nih.gov/pubmed/32945487 http://dx.doi.org/10.3892/or.2020.7730 |
Ejemplares similares
-
Immunosuppressive Treg cells acquire the phenotype of effector-T cells in chronic lymphocytic leukemia patients
por: De Matteis, Serena, et al.
Publicado: (2018) -
Unexpected low expression of platelet fibrinogen receptor in patients with chronic myeloproliferative neoplasms: how does it change with aspirin?
por: Lucchesi, Alessandro, et al.
Publicado: (2019) -
Exploring the ATR-CHK1 pathway in the response of doxorubicin-induced DNA damages in acute lymphoblastic leukemia cells
por: Ghelli Luserna Di Rorà, Andrea, et al.
Publicado: (2021) -
Germline CSF3R Variant in Chronic Myelomonocytic Leukemia: Linking Genetic Predisposition to Uncommon Hemorrhagic Symptoms
por: Bochicchio, Maria Teresa, et al.
Publicado: (2023) -
Sorafenib in the Treatment of Virus-Related HCC: Differences Between HCV and HBV
por: De Matteis, Serena, et al.
Publicado: (2021)