Flagellin shifts 3D bronchospheres towards mucus hyperproduction

Cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are associated with acute and chronic bacterial infections of the lung. Excessive differentiation of basal cells to mucus-producing goblet cells can result in mucus hyperproduction and loss of mucociliary clearance in the airways...

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Detalles Bibliográficos
Autores principales: Sprott, Richard F., Ritzmann, Felix, Langer, Frank, Yao, Yiwen, Herr, Christian, Kohl, Yvonne, Tschernig, Thomas, Bals, Robert, Beisswenger, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448433/
https://www.ncbi.nlm.nih.gov/pubmed/32847538
http://dx.doi.org/10.1186/s12931-020-01486-x

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