Cargando…

TLR9 induces colitis-associated colorectal carcinogenesis by regulating NF-κB expression levels

Chronic colorectal inflammation has been associated with colorectal cancer (CRC); however, its exact molecular mechanisms remain unclear. The present study aimed to investigate the effect of Toll-like receptor 9 (TLR9) on the development of colitis-associated CRC (CAC) through its regulation of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Qingtian, Zeng, Ling, Tang, Chaotao, Zhang, Zhendong, Chen, Youxiang, Zeng, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448563/ https://www.ncbi.nlm.nih.gov/pubmed/32863923 http://dx.doi.org/10.3892/ol.2020.11971

Ejemplares similares

Molecular mechanisms of Huanglian jiedu decoction on ulcerative colitis based on network pharmacology and molecular docking
por: Yang, Jing, et al.
Publicado: (2022)

Involvement of NF-κB/IL-6 Pathway in the Processing of Colorectal Carcinogenesis in Colitis Mice
por: Yang, Hang, et al.
Publicado: (2014)

Wogonoside prevents colitis-associated colorectal carcinogenesis and colon cancer progression in inflammation-related microenvironment via inhibiting NF-κB activation through PI3K/Akt pathway
por: Sun, Yang, et al.
Publicado: (2016)

Retrospective analysis of LNM risk factors and the effect of chemotherapy in early colorectal cancer: A Chinese multicenter study
por: Zeng, Chunyan, et al.
Publicado: (2020)

mRNA expression of TLR4, TLR9 and NF-κB in a neonatal murine model of necrotizing enterocolitis
por: Yin, Yiyu, et al.
Publicado: (2016)

Mechanism of Probiotic VSL#3 Inhibiting NF-κB and TNF-α on Colitis through TLR4-NF-κB Signal Pathway
por: WANG, Hui, et al.
Publicado: (2019)

Heavy-ion radiation-induced colitis and colorectal carcinogenesis in Il10(-/)(-) mice display co-activation of β-catenin and NF-κB signaling
por: Suman, Shubhankar, et al.
Publicado: (2022)

Quinic acid ameliorates ulcerative colitis in rats, through the inhibition of two TLR4‐NF‐κB and NF‐κB‐INOS‐NO signaling pathways
por: Ghasemi‐Dehnoo, Maryam, et al.
Publicado: (2023)

TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression
por: Gao, Caixia, et al.
Publicado: (2018)

Effect of betulinic acid administration on TLR-9/NF-κB /IL-18 levels in experimental liver injury
por: DOKUMACIOĞLU, Eda, et al.
Publicado: (2021)

Alhagi pseudalhagi Extract Exerts Protective Effects Against Intestinal Inflammation in Ulcerative Colitis by Affecting TLR(4)-Dependent NF-κB Signaling Pathways
por: Xu, Xiaoqin, et al.
Publicado: (2021)

Knockdown of ILK Alleviates High Glucose-Induced Damage of H9C2 Cells through TLR4/MyD88/NF-κB Pathway
por: Yin, Qiang, et al.
Publicado: (2022)

Colitis and Colorectal Carcinogenesis: The Focus on Isolated Lymphoid Follicles
por: Műzes, Györgyi, et al.
Publicado: (2022)

Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway
por: Zhou, Ping, et al.
Publicado: (2022)

Serum TLR9 and NF-κB Biochemical Markers in Patients with Acute Pancreatitis on Admission
por: Demirtas, Erdal, et al.
Publicado: (2020)

Kaempferide improves oxidative stress and inflammation by inhibiting the TLR4/IκBα/NF-κB pathway in obese mice
por: Tang, Heng, et al.
Publicado: (2021)

l-Isoleucine Administration Alleviates DSS-Induced Colitis by Regulating TLR4/MyD88/NF-κB Pathway in Rats
por: Mao, Xiangbing, et al.
Publicado: (2022)

Dietary Crocin Inhibits Colitis and Colitis-Associated Colorectal Carcinogenesis in Male ICR Mice
por: Kawabata, Kunihiro, et al.
Publicado: (2012)

Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis
por: Nishikawa, M, et al.
Publicado: (2005)

Dvl2 facilitates the coordination of NF‐κB and Wnt signaling to promote colitis‐associated colorectal progression
por: Tang, Feiyu, et al.
Publicado: (2021)

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue
por: ZHANG, JIAN-ZHENG, et al.
Publicado: (2014)

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue
por: Zhang, Jian-Zheng, et al.
Publicado: (2023)

Herb-Partitioned Moxibustion Regulates the TLR2/NF-κB Signaling Pathway in a Rat Model of Ulcerative Colitis
por: Wang, Xiaomei, et al.
Publicado: (2015)

Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis
por: Qu, Yifan, et al.
Publicado: (2021)

Inhibition of IRAK 1/4 alleviates colitis by inhibiting TLR 4/NF-κB pathway and protecting the intestinal barrier
por: Yan, Bo, et al.
Publicado: (2022)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis
por: Southern, Samantha L., et al.
Publicado: (2011)

NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis
por: Yao, J, et al.
Publicado: (2014)

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling
por: Sandor, Frantisek, et al.
Publicado: (2003)

Escherichia coli promotes DSS-induced murine colitis recovery through activation of the TLR4/NF-κB signaling pathway
por: Lu, Jiabao, et al.
Publicado: (2019)

The Effect of TLR9, MyD88, and NF-κB p65 in Systemic Lupus Erythematosus
por: Wang, Huanan, et al.
Publicado: (2022)

Elabela inhibits TRAF1/NF-κB induced oxidative DNA damage to promote diabetic foot ulcer wound healing
por: Hong, Yinghui, et al.
Publicado: (2023)

Comparison of some biochemical markers between early‐onset and late‐onset colorectal precancerous lesions: A single‐center retrospective study
por: Tang, Chao‐Tao, et al.
Publicado: (2022)

Fusobacterium nucleatum Facilitates M2 Macrophage Polarization and Colorectal Carcinoma Progression by Activating TLR4/NF-κB/S100A9 Cascade
por: Hu, Lijun, et al.
Publicado: (2021)

Epidermal p65/NF-κB signalling is essential for skin carcinogenesis
por: Kim, Chun, et al.
Publicado: (2014)

Attribution of NF-κB Activity to CHUK/IKKα-Involved Carcinogenesis
por: Li, Xin, et al.
Publicado: (2021)

Taraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer
por: Tang, Chao-Tao, et al.
Publicado: (2021)

Flower extract of Caragana sinica. ameliorates DSS-induced ulcerative colitis by affecting TLR4/NF-κB and TLR4/MAPK signaling pathway in a mouse model
por: Li, Ting, et al.
Publicado: (2021)

Tolerogenic dendritic cells and TLR4/IRAK4/NF-κB signaling pathway in allergic rhinitis
por: Kang, Chenglin, et al.
Publicado: (2023)

Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis
por: Interdonato, Livia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2o4k2d1av8a2ee2205u5emgg2q