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Performance of PCR/Electrospray Ionization-Mass Spectrometry on Whole Blood for Detection of Bloodstream Microorganisms in Patients with Suspected Sepsis

Blood culture (BC) often fails to detect bloodstream microorganisms in sepsis. However, molecular diagnostics hold great potential. The molecular method PCR/electrospray ionization-mass spectrometry (PCR/ESI-MS) can detect DNA from hundreds of different microorganisms in whole blood. The aim of the...

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Detalles Bibliográficos
Autores principales: Strålin, Kristoffer, Rothman, Richard E., Özenci, Volkan, Barkataki, Kieron, Brealey, David, Dhiman, Neelam, Poling, Lara, Kurz, Michael C., Limaye, Ajit P., LoVecchio, Frank, Lowery, Kristin, Miller, Loren G., Moran, Gregory J., Overcash, J. Scott, Parekh, Amisha, Peacock, W. Frank, Rivers, Emanuel P., Sims, Matthew, Stubbs, Amy M., Sundqvist, Martin, Ullberg, Måns, Carroll, Karen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7448645/
https://www.ncbi.nlm.nih.gov/pubmed/32641399
http://dx.doi.org/10.1128/JCM.01860-19